This report critically evaluates the effectiveness of e-cigarettes as a smoking cessation aid compared to nicotine replacement therapies (NRT), using Joanne's case scenario as a focal point. It assesses the strengths and limitations of existing research, including sample size, data collection methods, and potential biases, while also examining the research questions, design, and methods employed in studies on e-cigarette efficacy. The report highlights findings that suggest e-cigarettes can be an efficient therapy for quitting smoking, though concerns remain about the safety and long-term health implications, including the potential for addiction and lung cancer. Ultimately, the report concludes that while e-cigarettes may hold promise, more research is needed to fully understand their efficacy and safety before widespread clinical application can be recommended, suggesting a combined approach with other therapies may be more beneficial.