This report critically analyzes the effectiveness of e-cigarettes as a smoking cessation tool, drawing upon evidence-based research and case studies. The introduction establishes the need for a rigorous evaluation of e-cigarette efficacy, referencing relevant studies to address the clinical question of how e-cigarettes compare to other therapies like nicotine replacement therapy (NRT). The report assesses the strengths and limitations of the research, including the use of large samples, the emergence of e-cigarettes as a therapy, and the reliance on self-reported data. It examines research questions, designs, and methods, highlighting the use of cross-sectional surveys and ANOVA analysis. Findings suggest that e-cigarettes can be effective for some smokers, but the report also acknowledges limitations, such as the lack of clinical guidelines and potential health implications. The conclusion emphasizes the need for further research and cautions against using the current evidence to inform clinical practice without considering a combination of methods to aid in quitting smoking. The report is based on a case study and provides recommendations and insights into the role of e-cigarettes in smoking cessation.