This report provides an overview of Electronic Health Records (EHR) in nursing practice. It explores the systematic process of EHR, emphasizing their role in improving patient data management through connected networks. The report highlights workflow changes, focusing on evidence-based practice (EBP), communication and coordination, and the timeliness of documentation. It also delves into EHR design for healthcare, including rapid response e-health tools, drug prescription notification designs, and patient-centered interfaces. The rationale process and importance of clear medical record interfaces are discussed, along with the strategic planning of health information systems. The benefits of workflow changes, such as generating and compiling information, detecting health threats, and effective communication, are examined. Strategies for effective and safe patient satisfaction in EHR for nursing care practice are presented. The report also addresses assessing nurses' readiness for HIS and EHR systems, the need for collaboration, interoperability, and the role of EHR in improving diagnostics and outcomes, reducing errors, and managing risks. The conclusion emphasizes the effectiveness of EHR in providing real-time, patient-centered information, improving patient care, and coordinating care. The report references several studies and articles to support its findings.