This report provides an overview of the endocrine system, emphasizing its role in regulating metabolism, growth, and reproduction. It details health promotion strategies, including diet, exercise, and avoiding harmful substances like tobacco and excessive caffeine. The report also discusses age-related changes in hormone levels, such as the decline of estrogen in women and testosterone in men, and the impact of these changes on overall health. Furthermore, it highlights gender-related differences in hormonal profiles, with a focus on the impact of testosterone and estrogen. The report references several studies and articles, including those by La Perle & Dintzis (2018), Lavie et al. (2018), and Vitale et al. (2016), to support its findings. It concludes by encouraging readers to seek further information from healthcare professionals.