This position paper examines the integration of evidence-based practice (EBP) in nursing, emphasizing its importance for delivering quality care and improving patient outcomes. It highlights the historical context of EBP, tracing its roots back to Florence Nightingale and the evolution of nursing practices. The paper asserts the thesis that EBP, which combines research evidence, clinical expertise, and patient values, is essential for informed decision-making and optimal care. It also acknowledges potential limitations and counterarguments, such as the risk of overlooking non-empirical models and the challenges of applying EBP across diverse cultural groups and the impact of funding and insurance coverage. The paper then refutes these counterclaims, emphasizing the ongoing efforts of nursing professionals to integrate evidence with their clinical expertise, ultimately advocating for the continued adoption and refinement of EBP to advance the nursing discipline and improve healthcare delivery.