This report delves into the application of evidence-based practice (EBP) within the context of surgical wound care. It begins by highlighting the significance of EBP in improving healthcare quality and patient outcomes, emphasizing the integration of best practices, clinical expertise, and patient values. The report outlines the five key steps of EBP, including finding, appraising, and implementing research findings. It then explores procedural and propositional knowledge relevant to wound care, detailing historical contexts, assessment techniques, and the importance of standardized documentation to prevent surgical site infections. Recommendations are provided for infection prevention, including the use of prophylactic antibiotics and appropriate wound dressings. The report concludes by emphasizing the need for healthcare professionals to align their practices with evidence-based guidelines to ensure optimal surgical wound care and patient outcomes.