Evidence Based Practice Report: Rheumatoid Arthritis Treatment

This report focuses on Evidence-Based Practice (EBP) in healthcare, specifically addressing the treatment of Rheumatoid Arthritis. The report begins by defining EBP and its importance in improving patient outcomes, followed by an explanation of the PICO framework for formulating clinical questions. A specific clinical question is presented: the effectiveness of short-term, low-dose corticosteroids compared to NSAIDs in patients aged 45-60 with Rheumatoid Arthritis. The background of the study is provided, highlighting the side effects of NSAIDs. The report then outlines the PICO elements for the question. Finally, a research study by Zhang et al. (2019) is discussed, which suggests that corticosteroids can reduce pain and inflammation associated with Rheumatoid Arthritis by reducing pain response and minimizing inflammation and edema. References for the mentioned studies are also provided.

Running head: EVIDENCE BASED PRACTICE
EVIDENCE BASED PRACTICE
Name of the student:
Name of the university:
Author note

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EVIDENCE BASED PRACTICE
Discussion:
1. a) An evidence-based practice (EBP) is considered as any practice which relies on research
evidence for assistance and decision-making (Yingfeng et al., 2016). The importance of the
evidence based practice is that it aims to deliver the most suitable and effective care based on
the research so that patient outcomes can be improved.
b) The PICO process is a framework which is used in evidence based in order to frame and
answer a clinical or health care related question (Considine et al., 2017). The elements of the
process include population, invention, comparison and outcome. Sometimes type or time is used
for the type of the study.
c) In population of 45-60 with rheumatoid arthritis, is short-term low-dose corticosteroids is
effective compared to NSAIDS?
d) The background of the study is that in patients with rheumatoid arthritis NSAIDS can reduce
the pain of the arthritis but increase the feeling of nausea. The prime reason behind it is that
NSAIDS facilitate ulcer by interfering with the ability of stomach to protect itself from the
gastric acids as the protective barriers are compromised.
e) Population: population of 45-60 with rheumatoid arthritis
Intervention: short-term low-dose corticosteroids
Comparison: NSAIDS
Outcome: reduction of pain and nausea

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EVIDENCE BASED PRACTICE
f) Zhang, L., Huang, Y., Wu, C., Du, Y., Li, P., Wang, M., ... & Fan, B. (2019). Network
Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose
Glucocorticoids in Anti-rheumatoid Arthritis. Frontiers in Pharmacology, 10.
It is the best study to answer the question.
The researchers suggested that it reduces pain of rheumatoid Arthritis by minimizing
inflammation and edema associated with tumor. It depolarize the damaged nerve and reduce the
pain response.

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EVIDENCE BASED PRACTICE
References:
Considine, J., Shaban, R. Z., Fry, M., & Curtis, K. (2017). Evidence based emergency
nursing: designing a research question and searching the literature. International emergency
nursing, 32, 78-82.
Yingfeng, Z., Yan, H., Yanhong, G., Ying, G., & Zheng, Z. (2016). Application of
knowledge translation models in evidence-based nursing practice. Journal of Nursing Science,
(2), 36.
Zhang, L., Huang, Y., Wu, C., Du, Y., Li, P., Wang, M., ... & Fan, B. (2019). Network
Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose
Glucocorticoids in Anti-rheumatoid Arthritis. Frontiers in Pharmacology, 10.