This nursing assignment examines the use of fish oil as a treatment for osteoarthritis, focusing on a case study of a 65-year-old woman experiencing knee pain. The assignment utilizes the PICO framework to formulate a research question and conducts database searches in MEDLINE and CINAHL to find relevant articles. The student analyzes two key articles that explore the efficacy and safety of fish oil, including different dosages, in treating knee osteoarthritis. The findings suggest that fish oil, in both low and high doses, can improve knee movement and reduce pain for osteoarthritis patients. The assignment concludes that while more research is needed, the available evidence supports the use of fish oil as a potential treatment option, offering relief from joint pain and swelling.