This report is a systematic review investigating the impact of graduated compression stockings (GCS) on preventing deep vein thrombosis (DVT) in post-operative orthopaedic patients. A literature search was conducted using MEDLINE and CINAHL databases, focusing on studies related to GCS, DVT, and postoperative care. Four relevant articles were critically analyzed, revealing that while GCS may reduce DVT risks initially, the difference between GCS and standard therapy lacked significant statistical support. The review discusses the mechanism of action of GCS, its clinical implications, and highlights the need for multicenter randomized trials to confirm its effectiveness across broader populations. The study concludes that clinicians can consider GCS for DVT risk reduction in orthopaedic patients, but further research is necessary to validate these findings.