This report, prepared for a NUR2300 assignment at Griffith University, delves into the critical issue of pressure injuries (PIs) within healthcare settings. The report begins by defining the problem, highlighting its impact on patients and healthcare services, and emphasizing the need for prevention. It then presents a clinical question formulated using the PICO framework and discusses the relevant domain. A core component of the report involves an evidence search, identifying and summarizing several research articles, including their place on the evidence hierarchy, and justifying their selection based on the PICO terms and question domain. The report includes evidence summary tables for each article. The assignment also includes a critical appraisal of the research, and concludes with recommendations. The report uses the APA style. The report examines the prevalence, risk factors, and prevention of pressure injuries, and it synthesizes research knowledge to apply standards for the review and evaluation of research to appraise the highest level of evidence.