This report provides a comprehensive analysis of GlaxoSmithKline (GSK) plc's performance, evaluating its key performance indicators, challenges, and areas for improvement. The study begins with an overview of GSK's background, including its history and current position in the pharmaceutical industry. A critical review of relevant literature on financial, internal, and external analysis is presented. The report utilizes PESTEL analysis to examine GSK's external environment, revealing the impact of political, economic, social, technological, environmental, and legal factors. This is followed by an internal analysis using SWOT analysis to assess strengths, weaknesses, opportunities, and threats. Financial performance is evaluated using ratio analysis, including profitability, liquidity, and asset turnover ratios. The report also incorporates a balanced scorecard framework, focusing on strategic themes of business development and operational efficiency, with objectives, measures, and KPIs across financial, customer, internal business, and learning and development perspectives. The analysis culminates in findings and recommendations regarding GSK's overall performance and strategic direction.