This essay examines the significant health disparities between Aboriginal and Torres Strait Islander (ATSI) communities and the Anglo-Australian population. It highlights the widening gap in life expectancy and prevalence of diseases like cardiovascular infections, mental disorders, diabetes, and chronic respiratory infections within the ATSI communities. The essay delves into historical factors, particularly the impact of colonialism, land dispossession, racism, and discrimination, which have profoundly affected the health and well-being of the ATSI people. It discusses how these historical injustices have created barriers to healthcare access and influenced social determinants of health. The essay emphasizes the need for culturally sensitive and holistic solutions, including new policies and strategies to address the health inequalities. It also explores the roles of primary healthcare, government initiatives like the Closing the Gap program, and the importance of equitable, efficient, and effective healthcare frameworks. The analysis underscores the critical importance of addressing social determinants such as employment, education, and housing to achieve health equality. The essay references various studies and reports from organizations like the ABS, WHO, AIHW, and Australian Institute of Criminology to support its arguments.