This report provides a detailed analysis of the Hepatitis B pathogen, including its structure, replication process, and impact on the host. It explores the symptoms of the virus, its mechanisms for circumventing the host's defense systems, and various laboratory techniques used for its cultivation and detection, such as PCR. The report also discusses the diagnostic methods employed to identify and manage Hepatitis B, emphasizing the importance of hygiene, lifestyle choices, and medical interventions, including antiviral treatments, in controlling the virus. The report highlights key aspects of Hepatitis B, including its classification as a DNA virus, its replication through RNA intermediates, and its potential to integrate into host cells. The report also discusses the role of the virus in causing jaundice and the importance of monitoring factors such as antigen positivity and liver transplantation in the context of Hepatitis B management.