This report provides a comprehensive literature review on Industry 4.0, emphasizing its transformative impact on manufacturing. It begins with an executive summary and table of contents, followed by an introduction that highlights the evolution from Industry 3.0 to Industry 4.0, emphasizing automation, data exchange, and smart factories. The report details the system architecture, including layers like supervisory control, industrial network, cloud, and physical resources. It outlines the design principles of Industry 4.0, such as interconnection, information transparency, decentralized decisions, and technical assistance. The report also contrasts Industry 3.0 and 4.0, highlighting differences in cloud usage, big data analytics, IoT implementation, and data collection. It then explores the opportunities of Industry 4.0 from both micro and macro perspectives, including sustainable manufacturing, new business models, value creation networks, and improvements in equipment, human roles, organizational structures, processes, and product design. Finally, the report addresses the challenges of implementing Industry 4.0, such as rethinking organizational processes, understanding business cases, conducting successful pilots, and adapting company culture. The conclusion summarizes the revolutionary changes, advancements, and opportunities that Industry 4.0 brings to the industry.