This report delves into the realm of information systems and Enterprise Resource Planning (ERP) within the context of business operations, with a particular focus on Marks & Spencer. It initiates with a categorization of diverse information systems, including Decision Support Systems, Transaction Processing Systems, Management Information Systems, and Computer-Based Information Systems, elucidating their roles in supporting various business functions. The report then transitions to an in-depth exploration of ERP systems, explaining their integrated nature and outlining various modules such as Human Resource, Purchase, Inventory, Sales, Finance, CRM, Production, and Supply Chain Management. Furthermore, it highlights the tangible benefits of ERP implementation in real-world business scenarios, such as enhanced staff efficiency, cost-effectiveness, time savings, reduced errors, data security, improved customer service, and standardized business processes. The report concludes by emphasizing the significance of information systems and ERP for organizational success, accompanied by recommendations for effective implementation and utilization.