This case study focuses on Dorothy Miller, a 73-year-old woman with a history of cardiac failure, atrial fibrillation, diabetes, and other conditions, who presented with acute exacerbation of chronic heart failure and acute renal failure. The study details the initial assessments, revealing neurological, cardiovascular, and respiratory complications, including confusion, cool extremities, irregular pulse, hypertension, and low oxygen saturation. The pathophysiology discusses how atrial fibrillation led to pulmonary edema, exacerbated by her medical history of elevated cholesterol and diabetes. Interventions include pharmacological treatments like diuretics, beta-blockers, and intravenous electrolytes to manage cardiac dysfunction, fluid volume imbalance, and prevent renal failure. The priority is addressing cardiac dysfunction and atrial fibrillation to stabilize vital signs and mitigate immediate risks.