This essay delves into the multifaceted challenges encountered by international students, particularly those for whom English is a second language (ESL), within the context of US universities. It identifies language barriers as a primary obstacle, alongside issues of social support and academic adjustment. The essay examines the significance of English language programs (ELP) in addressing these challenges, emphasizing the diverse range of individual differences, such as personality, behavior, and motivation, that influence the learning process. It highlights critical factors like integrative motivation and the potential for marginalization, providing insights into the experiences of international students and the need for guidance and support programs. The study aims to identify the problems faced by international students whose first language is not English in their academics and their cultural lives in United States. The conclusion emphasizes the need for universities to provide proper guidance and orientation programs to assist international students in navigating the educational system and encourages the implementation of reading tests and improvements in ESL curricula.