This report delves into the multifaceted impact of life-limiting illnesses on individuals, encompassing physical, emotional, and spiritual dimensions. It explores the psychological disturbances associated with chronic conditions, including fear, anxiety, and the impact on family relationships and social life. The report emphasizes the significance of spiritual needs in healthcare, as defined by the WHO, and the crucial role of nurses in assessing and providing spiritual care. It highlights the importance of person-centered care, spiritual assessment, and allowing patients to practice religious rituals. The report also discusses the cultural and religious considerations in palliative care, and stresses the need for nurses to offer empathetic support and advocate for their patients' holistic well-being, considering both their physical and spiritual needs. References from various research papers are included.