CNA803 Assignment 2: Practice Change Proposal - Teen Mental Health
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Project
AI Summary
This project presents a practice change proposal aimed at addressing depression and bipolar disorder in teenagers by exploring the impact of lifestyle modifications. The proposal begins with an executive summary outlining the problem, which involves the increasing rates of depression and bipolar issues among teenagers, linked to unhealthy lifestyles and excessive screen time. A literature review supports the significance of the study, highlighting the role of lifestyle changes in managing these conditions. The project's primary aim is to identify effective lifestyle changes and assess their contribution to treating depression and bipolar disorder. Objectives include determining the causes of these issues, evaluating the impact of lifestyle interventions, and identifying challenges in implementing changes. The proposal outlines implementation theories, including the transgenic model, and discusses team members, timelines, and potential barriers. Expected outcomes include improved understanding of the causes and effective interventions. The project emphasizes the importance of a holistic approach to improve mental health outcomes for teenagers, which is vital for nursing students and healthcare professionals.

Practice change proposal
Table of Contents
Table of Contents
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1. Executive summary......................................................................................................................1
2. Background..................................................................................................................................1
2.1. Problem Overview...........................................................................................................1
2.2. Significance and quality of the evidence (literature review)...........................................1
2.3. Evidence of a gap/ shortfall in practice...........................................................................3
3. Project aims and objective (100)..................................................................................................3
3.1 Primary aim......................................................................................................................3
3.2 Objectives.........................................................................................................................3
4. Outcomes (200)............................................................................................................................3
5. Implementation theory/ models/ Frameworks (400)....................................................................4
6. Team members, timeline, budget, barriers (500).........................................................................4
6.1. Team members................................................................................................................4
6.2 Timeline............................................................................................................................4
6.3 Budget...............................................................................................................................4
6.4 Barriers and mitigation strategies.....................................................................................4
7. Evaluation (100)...........................................................................................................................4
8. Conclusion (100)..........................................................................................................................4
REFERENCES................................................................................................................................4
2. Background..................................................................................................................................1
2.1. Problem Overview...........................................................................................................1
2.2. Significance and quality of the evidence (literature review)...........................................1
2.3. Evidence of a gap/ shortfall in practice...........................................................................3
3. Project aims and objective (100)..................................................................................................3
3.1 Primary aim......................................................................................................................3
3.2 Objectives.........................................................................................................................3
4. Outcomes (200)............................................................................................................................3
5. Implementation theory/ models/ Frameworks (400)....................................................................4
6. Team members, timeline, budget, barriers (500).........................................................................4
6.1. Team members................................................................................................................4
6.2 Timeline............................................................................................................................4
6.3 Budget...............................................................................................................................4
6.4 Barriers and mitigation strategies.....................................................................................4
7. Evaluation (100)...........................................................................................................................4
8. Conclusion (100)..........................................................................................................................4
REFERENCES................................................................................................................................4

1. Executive summary
The current study is based on the topic of identifying the ways of changing lifestyle and its
contribution towards redressal of issues like depression and Bipolar. It has been seen that the
current lifestyle of teenager which comprises of feeling and thinking of being along and away
from others along with over depended on TV and other electronic measures for the purpose of
entertainment are the main reason that is creating issue of depression in Teenagers. Further, it
has been also seen that the issue of Bipolar is also increasing within teenager that is a manic
depression and comprise of mental illness that tend to brings servers high and low moods. Thus,
current investigation is undertaken in teenagers to have better understanding about the reason
behind occurring of depression and bipolar issues among teenagers along with ascertaining the
contribution of lifestyle changes on treatment of the issues like depression and bipolar. Apart
from this, a discussion about ascertain challenges that will be faced by teenagers while changing
lifestyle is also provided by current investigation. Apart from this, an implication about the team
members, budgets and role of team members has been also provided for better accomplishment
of current investigation.
2. Background
2.1. Problem Overview
The problem that has been analysed and redressed through current investigation comprises
of issue of depression and Bipolar in teenagers. It has been observed that there are mainly
reasons comprise of unhealthy and lonely lifestyle of teenagers along with family agreements
and high dependency on TV and other online means in place of actual and physical interaction
that us creating high issue and problem of depression and Bipolar in Teenager (Ponsoni & et. al.,
2020).
2.2. Significance and quality of the evidence (literature review)
Leading out current investigation is seemed significant and vital as it would facilitate and
lead out an effective analysis about the reason behind occurring of depression and bipolar issues
among teenagers. Beside this, current investigation is also seemed rationale as would lead to
better implication about the contribution of lifestyle changes on treatment of the issues like
depression and bipolar among teenagers along with factors which are the main reason for their
occurrence (Mansur & Rosenblat, 2020). Apart from this, the selection of current topic an
1
The current study is based on the topic of identifying the ways of changing lifestyle and its
contribution towards redressal of issues like depression and Bipolar. It has been seen that the
current lifestyle of teenager which comprises of feeling and thinking of being along and away
from others along with over depended on TV and other electronic measures for the purpose of
entertainment are the main reason that is creating issue of depression in Teenagers. Further, it
has been also seen that the issue of Bipolar is also increasing within teenager that is a manic
depression and comprise of mental illness that tend to brings servers high and low moods. Thus,
current investigation is undertaken in teenagers to have better understanding about the reason
behind occurring of depression and bipolar issues among teenagers along with ascertaining the
contribution of lifestyle changes on treatment of the issues like depression and bipolar. Apart
from this, a discussion about ascertain challenges that will be faced by teenagers while changing
lifestyle is also provided by current investigation. Apart from this, an implication about the team
members, budgets and role of team members has been also provided for better accomplishment
of current investigation.
2. Background
2.1. Problem Overview
The problem that has been analysed and redressed through current investigation comprises
of issue of depression and Bipolar in teenagers. It has been observed that there are mainly
reasons comprise of unhealthy and lonely lifestyle of teenagers along with family agreements
and high dependency on TV and other online means in place of actual and physical interaction
that us creating high issue and problem of depression and Bipolar in Teenager (Ponsoni & et. al.,
2020).
2.2. Significance and quality of the evidence (literature review)
Leading out current investigation is seemed significant and vital as it would facilitate and
lead out an effective analysis about the reason behind occurring of depression and bipolar issues
among teenagers. Beside this, current investigation is also seemed rationale as would lead to
better implication about the contribution of lifestyle changes on treatment of the issues like
depression and bipolar among teenagers along with factors which are the main reason for their
occurrence (Mansur & Rosenblat, 2020). Apart from this, the selection of current topic an
1
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undertaking of current investigation is also vital from personal view point of researcher as it
effective meet the personal interest and academic purpose. Beside this, conduction of current
investigation also ensures improvement in the skills and managerial competencies of the
researcher. Further, to evaluate about the topic of ways of changing lifestyle and its contribution
towards redressal of issues like depression and Bipolar along with analysing present information
on issues of depression and Bipolar implication of analysis of secondary data is made which is
provided below under the heading of literature review.
Literature review
As per the view point of D'Arcy Lyness, (2021), Bipolar disorder is one of the main
condition that lead to depressive disorders and affects the brain function of a person. Further, it
has been find out that still the exact cause and remain behind the bipolar disorder is not their but
some biochemical, genetic and environmental factors are their which lead to issue of bipolar and
depression in teenagers. It has been observed that lifestyle of a teenager comprises of habit of
smoking and along with feeling of loneliness lead by some family disagreement or not having
much interaction due to reliance on TV and other online mode of entertainment are the main
reason of Bipolar and depression in teenagers (Liao & Pan, 2020).
Further, it has been also analysed as per the view point of Kellner, C.H. and Majoka, M.A.,
(2020), threat positive lifestyle made a vital contribution in treatment of the issues like
depression and bipolar as it has been seen that maintaining a healthy lifestyle and a consistent
routine can help a teenager to control manic and depressive episode. Thus, positive lifestyle
plays a vital role in controlling and mitigating the issue of bipolar and depression. Further, it has
been seen that the main symptoms and issues related with issue of Bipolar comprises of racing
speech and thoughts along with increased level of energy towards violation along with decreased
need for sleep. Beside this, a high level of elevated mood and having exaggerated optimism
along with reflecting a high level of excessive irritability in parallel with having aggressive
behaviour, and impatience is also comprising as main symptoms of Bipolar (Bahji & Vazquez,
2021).
Apart from this, an analysis about the symptoms of depression is also evaluated on the
basis of the information provided by Aslan, I.H. and Baldwin, D.S., (2021), which mainly
comprises of the loss of interest in usual activities along with prolonged sad or irritable mood.
Beside this, the teenagers suffering for depression also have a feeling of loss of energy or fatigue
2
effective meet the personal interest and academic purpose. Beside this, conduction of current
investigation also ensures improvement in the skills and managerial competencies of the
researcher. Further, to evaluate about the topic of ways of changing lifestyle and its contribution
towards redressal of issues like depression and Bipolar along with analysing present information
on issues of depression and Bipolar implication of analysis of secondary data is made which is
provided below under the heading of literature review.
Literature review
As per the view point of D'Arcy Lyness, (2021), Bipolar disorder is one of the main
condition that lead to depressive disorders and affects the brain function of a person. Further, it
has been find out that still the exact cause and remain behind the bipolar disorder is not their but
some biochemical, genetic and environmental factors are their which lead to issue of bipolar and
depression in teenagers. It has been observed that lifestyle of a teenager comprises of habit of
smoking and along with feeling of loneliness lead by some family disagreement or not having
much interaction due to reliance on TV and other online mode of entertainment are the main
reason of Bipolar and depression in teenagers (Liao & Pan, 2020).
Further, it has been also analysed as per the view point of Kellner, C.H. and Majoka, M.A.,
(2020), threat positive lifestyle made a vital contribution in treatment of the issues like
depression and bipolar as it has been seen that maintaining a healthy lifestyle and a consistent
routine can help a teenager to control manic and depressive episode. Thus, positive lifestyle
plays a vital role in controlling and mitigating the issue of bipolar and depression. Further, it has
been seen that the main symptoms and issues related with issue of Bipolar comprises of racing
speech and thoughts along with increased level of energy towards violation along with decreased
need for sleep. Beside this, a high level of elevated mood and having exaggerated optimism
along with reflecting a high level of excessive irritability in parallel with having aggressive
behaviour, and impatience is also comprising as main symptoms of Bipolar (Bahji & Vazquez,
2021).
Apart from this, an analysis about the symptoms of depression is also evaluated on the
basis of the information provided by Aslan, I.H. and Baldwin, D.S., (2021), which mainly
comprises of the loss of interest in usual activities along with prolonged sad or irritable mood.
Beside this, the teenagers suffering for depression also have a feeling of loss of energy or fatigue
2
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along with feelings of guilt or worthlessness which lead to negative impact on their mental and
physical health all together with drop in grades and inability to concentrate and experience
pleasure (Citrome, 2020). Thus, an analysis can be made out that both bipolar and depression are
creating many problems and issue in the life of teenagers comprises of enhanced feeling of
anger, worry, and anxiety that is mainly due to some past trauma or a lifestyle where they feel
lonely and having some trouble in adjusting socially along with lack of proper social and
emotional supports.
2.3. Evidence of a gap/ shortfall in practice
On the basis of evidence provided by analysis of secondary information it has been analysed
that sufficient amount of information is their about the main symptoms and issues like depression
and Bipolar but still information about the their main cause and contribution of ways of
changing lifestyle towards redressal of issues like depression and Bipolar is lacking, therefore,
the main shortfall and research gap is identified on the basis of above stated literature review
comprises of lack of information about the reason behind occurring of depression and bipolar
issues among teenagers along with the with factors which called for change in lifestyle as the
main reason for their occurrence. Therefore, current investigation is undertaken with the aim of
identifying the ways of changing lifestyle and its contribution towards redressal of issues like
depression and Bipolar within teenagers.
3. Project aims and objective
3.1 Primary aim
The aim of current investigation is “To identify the ways of changing lifestyle and its
contribution towards redressal of issues like depression and Bipolar”. A study on teenagers.
3.2 Objectives
To determine the reason behind occurring of depression and bipolar issues among
teenagers.
To ascertain the contribution of lifestyle changes on treatment of the issues like
depression and bipolar among teenagers along with factors which are the main reason for
their occurrence.
To ascertain challenges that will be faced by teenagers while changing lifestyle.
3
physical health all together with drop in grades and inability to concentrate and experience
pleasure (Citrome, 2020). Thus, an analysis can be made out that both bipolar and depression are
creating many problems and issue in the life of teenagers comprises of enhanced feeling of
anger, worry, and anxiety that is mainly due to some past trauma or a lifestyle where they feel
lonely and having some trouble in adjusting socially along with lack of proper social and
emotional supports.
2.3. Evidence of a gap/ shortfall in practice
On the basis of evidence provided by analysis of secondary information it has been analysed
that sufficient amount of information is their about the main symptoms and issues like depression
and Bipolar but still information about the their main cause and contribution of ways of
changing lifestyle towards redressal of issues like depression and Bipolar is lacking, therefore,
the main shortfall and research gap is identified on the basis of above stated literature review
comprises of lack of information about the reason behind occurring of depression and bipolar
issues among teenagers along with the with factors which called for change in lifestyle as the
main reason for their occurrence. Therefore, current investigation is undertaken with the aim of
identifying the ways of changing lifestyle and its contribution towards redressal of issues like
depression and Bipolar within teenagers.
3. Project aims and objective
3.1 Primary aim
The aim of current investigation is “To identify the ways of changing lifestyle and its
contribution towards redressal of issues like depression and Bipolar”. A study on teenagers.
3.2 Objectives
To determine the reason behind occurring of depression and bipolar issues among
teenagers.
To ascertain the contribution of lifestyle changes on treatment of the issues like
depression and bipolar among teenagers along with factors which are the main reason for
their occurrence.
To ascertain challenges that will be faced by teenagers while changing lifestyle.
3

4. Outcomes
The main outcome and result of current investigation would comprise of having an
improved information about the reason behind occurring of depression and bipolar issues among
teenagers so that timely action could be taken to redress and overcome these issues. Apart from
this, leading out current investigation would also lead to improved information about the
contribution made by change in lifestyle in redressing and overcoming this severe issue of
depression and Bipolar in teenagers. Thus, the main finding and outcome of current investigation
is based on getting a better understanding about the issue of depression and bipolar in teenage
along with analysing the reasons that leading enhanced chances of theses problem in individuals.
Apart from this, the main outcome of current investigation would comprise of a better analysis of
contribution made by change in lifestyle in redressing and overcoming the issue of depression
and bipolar in Individuals.
5. Implementation theory/ models/ Frameworks (400)
As per this, it is analysing that the condition or the situation which is being significantly play
some diverse role in the depression and the bipolar in the teenage along with the leading change
which create some of the issues in their pattern of life. In this, the overall analysis state about
some of the implementation theory or models or framework which help to create the intervention
channel in such a way which reduce the complications and produce a prevention technique for
controlling and minimising the factors which may associated with the patient or any individual
who is facing the issues of depression and bipolar disorders.
Transgenic model: In this, the major depression disorder is as creating the mental illness the
significant morbidity and mortality. Moreover, the growing number of studies and research is
well identified that the transgenic model is useful in this. This model state about the factors
which is associated with the depression and anxiety in this the depression are usually caused due
to the serotonin receptor where the excitatory neurotransmitter not segregated or accumulated in
such order which help to provide relaxation to the body. As per this some of the excitatory
neurotransmitters are acetylcholine and many more which plays significant role in this by
providing the relaxation and a continuous REM cycle for sleeping and NON-REM cycle for the
NON rapid eye movement. As per this, all are used to create some of the tends in the Serotonin
in agents which are commonly used to treat the depression and decrease 5-HT which play a
pathophysiological role in the major depression causes. As per this, the most genetic model of
4
The main outcome and result of current investigation would comprise of having an
improved information about the reason behind occurring of depression and bipolar issues among
teenagers so that timely action could be taken to redress and overcome these issues. Apart from
this, leading out current investigation would also lead to improved information about the
contribution made by change in lifestyle in redressing and overcoming this severe issue of
depression and Bipolar in teenagers. Thus, the main finding and outcome of current investigation
is based on getting a better understanding about the issue of depression and bipolar in teenage
along with analysing the reasons that leading enhanced chances of theses problem in individuals.
Apart from this, the main outcome of current investigation would comprise of a better analysis of
contribution made by change in lifestyle in redressing and overcoming the issue of depression
and bipolar in Individuals.
5. Implementation theory/ models/ Frameworks (400)
As per this, it is analysing that the condition or the situation which is being significantly play
some diverse role in the depression and the bipolar in the teenage along with the leading change
which create some of the issues in their pattern of life. In this, the overall analysis state about
some of the implementation theory or models or framework which help to create the intervention
channel in such a way which reduce the complications and produce a prevention technique for
controlling and minimising the factors which may associated with the patient or any individual
who is facing the issues of depression and bipolar disorders.
Transgenic model: In this, the major depression disorder is as creating the mental illness the
significant morbidity and mortality. Moreover, the growing number of studies and research is
well identified that the transgenic model is useful in this. This model state about the factors
which is associated with the depression and anxiety in this the depression are usually caused due
to the serotonin receptor where the excitatory neurotransmitter not segregated or accumulated in
such order which help to provide relaxation to the body. As per this some of the excitatory
neurotransmitters are acetylcholine and many more which plays significant role in this by
providing the relaxation and a continuous REM cycle for sleeping and NON-REM cycle for the
NON rapid eye movement. As per this, all are used to create some of the tends in the Serotonin
in agents which are commonly used to treat the depression and decrease 5-HT which play a
pathophysiological role in the major depression causes. As per this, the most genetic model of
4
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depression is based on manipulating of 5-HT system. To this, it is well analysed that the
condition of depression or bipolar is directly associated with the physiological condition of
serotonin receptor. In this, the serotonin plays a vital role in the development of sleeping cycle
and REM cycle. They used to maintain the hormone and other associated channel which provide
relaxation which include the body forming situation and these all analysis is useful to reduce the
complications by maintaining the serotonin level in the body (Rosenblat and et. al., 2019).
6. Team members, timeline, budget, barriers (500)
6.1. Team members
In this, identified team member which is associated with the health and medical team to
provide some of the basic facilities to remove eradicate the issue which is faced by patients. In
this, the team member which is play concluded part in decreasing the above normal it is which is
play an unnecessary role in the formation of issues and problems and create the situation worst
and more dignified. As per this, the team member which is associated with the healthcare sectors
are doctor, physician, nurse, or pharmacist and many more. They play a vital role in the
formulation of retaliation program or intervention which is associated with the depression and
bipolar disorder .
6.2 Timeline
The timeline is defined as the set of identified time set which is used to eradicate the issue
which is persist for the prolonged period. As per the depression and bipolar disorder and a
disease which is comprise their life. As per depending on the situation and the patient potential
and how they use the effective treatment for proper medication to overcome from this issue. The
timeline which is placed for the treatment is above 6 months because of proper eradication of the
issues. In the context with the healthcare sector, some of the disease which are not fixed with the
proper eradication of timeline. Because it's all depends on the patient scenario and overall
complications. As per this, the proper eradication of the disease is well analysed by appropriate
diagnosis and by the self-management of the patient (Lotfaliany and et. al., 2018).
6.3 Budget
The budget is usually shipped by the government to create the intervention which is useful for
the patient to overcome from this disease. This disease is associated with the brain disorder and
if this persist for the longer of period of time this is create the life-threatening issues. In order to
5
condition of depression or bipolar is directly associated with the physiological condition of
serotonin receptor. In this, the serotonin plays a vital role in the development of sleeping cycle
and REM cycle. They used to maintain the hormone and other associated channel which provide
relaxation which include the body forming situation and these all analysis is useful to reduce the
complications by maintaining the serotonin level in the body (Rosenblat and et. al., 2019).
6. Team members, timeline, budget, barriers (500)
6.1. Team members
In this, identified team member which is associated with the health and medical team to
provide some of the basic facilities to remove eradicate the issue which is faced by patients. In
this, the team member which is play concluded part in decreasing the above normal it is which is
play an unnecessary role in the formation of issues and problems and create the situation worst
and more dignified. As per this, the team member which is associated with the healthcare sectors
are doctor, physician, nurse, or pharmacist and many more. They play a vital role in the
formulation of retaliation program or intervention which is associated with the depression and
bipolar disorder .
6.2 Timeline
The timeline is defined as the set of identified time set which is used to eradicate the issue
which is persist for the prolonged period. As per the depression and bipolar disorder and a
disease which is comprise their life. As per depending on the situation and the patient potential
and how they use the effective treatment for proper medication to overcome from this issue. The
timeline which is placed for the treatment is above 6 months because of proper eradication of the
issues. In the context with the healthcare sector, some of the disease which are not fixed with the
proper eradication of timeline. Because it's all depends on the patient scenario and overall
complications. As per this, the proper eradication of the disease is well analysed by appropriate
diagnosis and by the self-management of the patient (Lotfaliany and et. al., 2018).
6.3 Budget
The budget is usually shipped by the government to create the intervention which is useful for
the patient to overcome from this disease. This disease is associated with the brain disorder and
if this persist for the longer of period of time this is create the life-threatening issues. In order to
5
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this, it is better analysing that the budget or the fund which is initiated by the government or the
private organisation is prepare some of the chat plan or the gang chat in order to taking the aspect
of previous funding and analysis of the population. The number of populations which is faces
this issue as according to this the budgeting and funds are initiated.
6.4 Barriers and mitigation strategies
While creating the proper treatment and appropriate management for the disease. Some of the
barrier which may be create the factors in the delivering of quality of care and the quality of
health to the patient. Some of these are cultural barriers and several populations which is also act
as a barrier. In this, the mitigation strategies which is used to follows are equally divided the
patient group and delivering of the care with their proper medication and treatment. This strategy
is always useful in every sector because the segmentation is only initial point which helps to
provide equal and appropriate treatment with patient (Gururajan and et. al., 2019).
7. Evaluation (100)
As per the above analysis, this is well stated that the condition of depression and bipolar
disorder is associated with the brain disease in which the person is not able to remember all the
things for the longer period. In this case, the proper care and appropriate treatment is needed for
the individual to recover or overcome from these issues. As per the government use to create
some of the interventions and model which helps to implies to understand the physiological
condition of the patient by providing best care treatment and the high standard quality
improvement which is related with the healthcare sectors (Putnam and et. al., 2017).
8. Conclusion
Based on current investigation, a conclusion can be made out that problem of bipolar and
depression is increasing within the teenagers which is leading out many issues and negative
implication on their mental and physical health. Beside this it has been summarised that having a
feeling of loneliness and family disagreement along with difficult in interacting with peers and
other aspects of society in form of lack of mental supports are the main reasons which are
creating and leading out issue of bipolar and depression in individuals. Further, it has been also
concluded that a vital contribution is lead out change in lifestyle and having positive habits of
eating and sleeping in reducing and mitigating the risk and issue of depression and bipolar in
individuals.
6
private organisation is prepare some of the chat plan or the gang chat in order to taking the aspect
of previous funding and analysis of the population. The number of populations which is faces
this issue as according to this the budgeting and funds are initiated.
6.4 Barriers and mitigation strategies
While creating the proper treatment and appropriate management for the disease. Some of the
barrier which may be create the factors in the delivering of quality of care and the quality of
health to the patient. Some of these are cultural barriers and several populations which is also act
as a barrier. In this, the mitigation strategies which is used to follows are equally divided the
patient group and delivering of the care with their proper medication and treatment. This strategy
is always useful in every sector because the segmentation is only initial point which helps to
provide equal and appropriate treatment with patient (Gururajan and et. al., 2019).
7. Evaluation (100)
As per the above analysis, this is well stated that the condition of depression and bipolar
disorder is associated with the brain disease in which the person is not able to remember all the
things for the longer period. In this case, the proper care and appropriate treatment is needed for
the individual to recover or overcome from these issues. As per the government use to create
some of the interventions and model which helps to implies to understand the physiological
condition of the patient by providing best care treatment and the high standard quality
improvement which is related with the healthcare sectors (Putnam and et. al., 2017).
8. Conclusion
Based on current investigation, a conclusion can be made out that problem of bipolar and
depression is increasing within the teenagers which is leading out many issues and negative
implication on their mental and physical health. Beside this it has been summarised that having a
feeling of loneliness and family disagreement along with difficult in interacting with peers and
other aspects of society in form of lack of mental supports are the main reasons which are
creating and leading out issue of bipolar and depression in individuals. Further, it has been also
concluded that a vital contribution is lead out change in lifestyle and having positive habits of
eating and sleeping in reducing and mitigating the risk and issue of depression and bipolar in
individuals.
6

REFERENCES
Books and journal
Aslan, I.H. & Baldwin, D.S., (2021). Ruminations and their correlates in depressive episodes:
Between-group comparison in patients with unipolar or bipolar depression and healthy
controls. Journal of Affective Disorders, 280, pp.1-6.
Bahji, A. & Vazquez, G., (2021). Comparative Efficacy and Tolerability of Adjunctive
Pharmacotherapies for Acute Bipolar Depression: A Systematic Review and Network
Meta-analysis. The Canadian Journal of Psychiatry, 66(3), pp.274-288.
Citrome, L., (2020). Food and Drug Administration–Approved Treatments for Acute Bipolar
Depression: What We Have and What We Need. Journal of Clinical
Psychopharmacology, 40(4), pp.334-338.
Kellner, C.H. & Majoka, M.A., (2020). Electroconvulsive Therapy as an Evidence-Based
Treatment for Acute Depression in Bipolar Disorder. The journal of ECT, 36(3), p.e33.
Liao, J.W. & Pan, J.Y., (2020). Comparative analysis of serum glutamate and gamma-
aminobutyric acid levels in patients with bipolar depressive disorder and major
depression disorder. Zhonghua yi xue za zhi, 100(23), pp.1800-1804.
Mansur, R.B. & Rosenblat, J.D., (2020). Leptin mediates improvements in cognitive function
following treatment with infliximab in adults with bipolar
depression. Psychoneuroendocrinology, 120, p.104779.
Ponsoni, A. & et. al., (2020). The effects of cognitive reserve and depressive symptoms on
cognitive performance in major depression and bipolar disorder. Journal of Affective
Disorders, 274, pp.813-818.
Putnam and et. al., 2017. Clinical phenotypes of perinatal depression and time of symptom onset:
analysis of data from an international consortium. The Lancet Psychiatry, 4(6), pp.477-
485.
Gururajan and et. al., 2019. The future of rodent models in depression research. Nature Reviews
Neuroscience, 20(11), pp.686-701.
Lotfaliany and et. al., 2018. Depression and chronic diseases: Co-occurrence and communality of
risk factors. Journal of affective disorders, 241, pp.461-468.
Rosenblat and et. al., 2019. Oral ketamine for depression: a systematic review. The Journal of
clinical psychiatry, 80(3), pp.0-0.
Online:
D'Arcy Lyness, (2021). Bipolar Disorder. [Online] Available Through:<
https://kidshealth.org/en/teens/bipolar.html#:~:text=Environmental%20factors%20may
%20play%20a,can%20set%20off%20an%20episode. >.
7
Books and journal
Aslan, I.H. & Baldwin, D.S., (2021). Ruminations and their correlates in depressive episodes:
Between-group comparison in patients with unipolar or bipolar depression and healthy
controls. Journal of Affective Disorders, 280, pp.1-6.
Bahji, A. & Vazquez, G., (2021). Comparative Efficacy and Tolerability of Adjunctive
Pharmacotherapies for Acute Bipolar Depression: A Systematic Review and Network
Meta-analysis. The Canadian Journal of Psychiatry, 66(3), pp.274-288.
Citrome, L., (2020). Food and Drug Administration–Approved Treatments for Acute Bipolar
Depression: What We Have and What We Need. Journal of Clinical
Psychopharmacology, 40(4), pp.334-338.
Kellner, C.H. & Majoka, M.A., (2020). Electroconvulsive Therapy as an Evidence-Based
Treatment for Acute Depression in Bipolar Disorder. The journal of ECT, 36(3), p.e33.
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