This essay discusses Major Depressive Disorder (MDD), arguing that women are the primary victims compared to men. It explores various mood disorders and highlights the prevalence of depression, particularly MDD, among women, citing statistics showing a higher diagnosis rate. Factors such as social pressure, income inequality, gender-based violence, and cultural biases contribute to this disparity. The essay also addresses the societal challenges faced by women with MDD, including inadequate support in educational institutions and the stigma surrounding mental health. It emphasizes the importance of raising awareness and providing support to those affected, advocating for a shift in societal perceptions of mental health and the need for empathy and understanding. The essay concludes by highlighting the need for acceptance and recovery rather than succumbing to poor mental health.