Medication Information Report: Detailed Case Study Analysis Solution

This report presents detailed medication information for a specific case study involving a 25-year-old single mother with hypothyroidism, Type 1 Diabetes, and an ear infection. The report covers four medications: Eutroxsig (levothyroxine sodium), Chloramphenicol, Ibuprofen, and Humalog (insulin lispro). For each medication, the report outlines the mode of action, common side effects, contraindications, and recommended administration guidelines. References are provided to support the information. The assignment is a response to a case study where the patient is prescribed these medications. The report is aimed at providing concise and relevant information about the drugs used in the case study.

Medication Information
For Case Study
Name of Students
Name of University
Author’s Note

MEDICATION INFORMATION
EUTROXSIG
MODE OF ACTION: It has levothyroxine sodium for
active ingredient, which acts as a replacement of thyroid
hormone (Walsh, 2016).
SIDE EFFECTS: Anxiety, Restlessness, Sleep
disturbances.
CONTRAINDICATION: Hyperthyroidism, Heart
problems, hypersensitivity.
ADMINISTRATION: 100 mg daily (Tga.gov.au., 2020).
CHLORAMPHENICOL
MODE OF ACTION: Chloramphenicol
inactivates the bacterial protein synthesis by
inhibiting protein chain elongation. It is
bacteriostatic.
SIDE EFFECTS: Diarrhoea, nausea, mental
disturbances, Anorexia.
CONTRAINDICATION: Anaemia, Bone
marrow abnormalities, decreased platelets,
hereditary liver disorder.
ADMINISTRATION: Four times a day.
(Dinos et al., 2016).
IBUPROFEN
MODE OF ACTION: Ibuprofen acts by
inhibiting the cyclooxygenase enzymes,
thus causing an analgesic effect.
SIDE EFFECTS: Heartburn,
constipation, dizziness, rashes.
CONTRAINDICATION: Salicylate
hypersensitivity, NSAID
hypersensitivity.
ADMINISTRATION: 200 mg three
times a day.
(Irvine, Afrose & Islam, 2018).
HUMALOG
MODE OF ACTION: Humalog,
also called insulin lispro is an
insulin analog that helps in
lowering the blood glucose level.
SIDE EFFECTS:
Hypoglycaemia may occur,
causing, nausea, shivers, sweats
and seizures.
CONTRAINDICATION: Renal
impairment, Diabetic
ketoacidosis, hepatic disease.
ADMINISTRATION: Four units
before meals, three times a day.
(de la Peña et al., 2016)
Eutroxsig prescribed for
hypothyroidism.
Chloramphenicol prescribed for ear
infection.
Humalog prescribed for
Diabetes.
Ibuprofen prescribed for pain.
Ibuprofen can
change the patient’s
blood sugar. Since
the patient already
has diabetes, this
should be
monitored (Vashist,
& Luong, 2017). . Ibuprofen and
Chloramphenicol are
found to be synergistic
in action and may be
useful in effective
treatment in many
bacterial infections
(Chan et al., 2017)
Chloramphenicol often has many adverse
effects and aids in growth of antibiotic
resistant bacteria. To avoid the side
effects, this drug may be reconsidered for
safer alternatives (Olajide et al., 2018).

Reference
Chan, E. W. L., Yee, Z. Y., Raja, I., & Yap, J. K. Y. (2017). Synergistic effect of non-steroidal anti-
inflammatory drugs (NSAIDs) on antibacterial activity of cefuroxime and chloramphenicol against
methicillin-resistant Staphylococcus aureus. Journal of global antimicrobial resistance, 10, 70-74.
de la Peña, A., Seger, M., Soon, D., Scott, A. J., Reddy, S. R., Dobbins, M. A., ... & Linnebjerg, H.
(2016). Bioequivalence and comparative pharmacodynamics of insulin lispro 200 U/mL relative to
insulin lispro (Humalog®) 100 U/mL. Clinical pharmacology in drug development, 5(1), 69-75.
Dinos, G. P., Athanassopoulos, C. M., Missiri, D. A., Giannopoulou, P. C., Vlachogiannis, I. A.,
Papadopoulos, G. E., ... & Kalpaxis, D. L. (2016). Chloramphenicol derivatives as antibacterial and
anticancer agents: historic problems and current solutions. Antibiotics, 5(2), 20.
Irvine, J., Afrose, A., & Islam, N. (2018). Formulation and delivery strategies of ibuprofen: challenges
and opportunities. Drug development and industrial pharmacy, 44(2), 173-183.
Olajide, T. G., Aremu, K. S., Esan, O. T., Dosunmu, A. O., & Raji, M. M. (2018). Topical ear drop self-
medication practice among the Ear, Nose, and Throat patients in Ido Ekiti, Nigeria: A cross-sectional
study. Annals of African medicine, 17(2), 70.
Tga.gov.au. (2020). Retrieved 18 March 2020, from https://www.tga.gov.au/sites/default/files/auspar-
thyroxine-sodium-140612.pdf.
Vashist, S. K., & Luong, J. H. (2017). Blood glucose monitoring devices. In Point-of-care Glucose
Detection for Diabetic Monitoring and Management (pp. 29-58). CRC Press.
Walsh, J. P. (2016). Managing thyroid disease in general practice. Medical Journal of Australia, 205(4),
179-184.