This report examines medication safety, focusing on the causes and effects of medication errors within healthcare settings. It highlights the significant role of human factors, such as lack of pharmacological knowledge, fatigue, and the use of ambiguous abbreviations, in contributing to these errors. The consequences of medication errors are far-reaching, impacting both patients (leading to prolonged hospitalization, increased costs, and potential harm) and healthcare providers (resulting in feelings of guilt and inadequacy). The report outlines the Australian Commission on Safety and Quality in Health Care's (ACSQHC) five key strategies aimed at improving medication safety, including governance and system standards, accurate documentation, medication process management, continuous medication management, and patient communication. Furthermore, it emphasizes the critical role of nurses in minimizing medication errors through compliance with professional standards, mentorship, and reporting of near misses. The report concludes that addressing predictable problems like fatigue and knowledge gaps, along with adherence to guidelines, is essential for reducing medication errors and preventing adverse drug events.