This report focuses on Quality Use of Medicines (QUM) and strategies to reduce medication errors within healthcare settings. It begins with an overview of QUM, its origins in the National Medicines Policy, and its patient-centered approach to ensuring the judicious, appropriate, safe, and efficacious use of medications. The report highlights the risks associated with medication errors, including increased healthcare costs, morbidity, and mortality, and identifies common causes such as lack of patient knowledge and poor healthcare practices. It emphasizes the importance of adhering to the National Safety and Quality Health Service Standard 4: Medication Safety and explores various strategies to mitigate errors. These include thorough patient assessments, continuous monitoring of treatment outcomes, patient education, medication reconciliation, and the use of computerized systems for clinical warnings. The report references key sources and provides a comprehensive overview of medication safety in healthcare.