This report presents a detailed Mental State Examination of a patient identified as Mr. Jones, who is experiencing symptoms of depression and anxiety following a separation from his wife. The examination covers various aspects of his mental state, including appearance, behavior, communication, affect, perceptions, cognition, insight, and judgment. The report details Mr. Jones's social withdrawal, lack of motivation, and increased alcohol consumption. It includes an ISBAR clinical handover, background information, a diagnosis of acute depression and anxiety, and recommendations for treatment, such as cognitive behavioral therapy (CBT) and antidepressant medications. The assessment highlights the patient's avoidance of eye contact, psychomotor retardation, blank facial expressions, and difficulties with memory recall. The report also addresses potential risk issues like lack of concentration, sleep problems, and possible liver issues related to alcohol consumption, providing a comprehensive overview of Mr. Jones's condition and suggesting appropriate interventions.