This report provides a comprehensive clinical reflection on the mental health assessment of Alison, a 38-year-old woman experiencing low mood, as presented in a video case scenario. The report details the GP's assessment process, emphasizing the gathering of patient history, mood evaluation, behavioral changes, and cognitive function. It highlights the use of the Mental Status Examination (MSE) to collect cues and symptoms suggestive of depression. The report further explores the GP's risk assessment and the patient's past psychiatric history, including previous episodes and coping mechanisms. The analysis underscores the importance of clinical reasoning cycle in interpreting information, forming a diagnosis, and making informed decisions. The report concludes by emphasizing the critical role of MSE and clinical reasoning skills for mental health nurses in assessing and managing patients' conditions, ultimately leading to improved patient outcomes. The provided references support the evidence-based practice discussed within the reflection.