This case study focuses on Linda, a 21-year-old woman diagnosed with clinical depression, suicide ideation, and insomnia. The assignment explores the application of holistic nursing principles, including a biopsychosocial assessment, within the APIE framework (Assess, Plan, Implement, Recheck, Evaluate). It critically examines the effectiveness of interventions such as Cognitive Behavioral Therapy (CBT), pharmacological treatments, and strategies for managing insomnia to improve depression outcomes. The study references the Nursing and Midwifery Council (NMC) standards, NICE guidelines, and the Patient-Centered Assessment Method (PCAM) to provide a comprehensive approach to Linda's care, considering her past trauma and lived experiences. The paper emphasizes the importance of a holistic approach in assessing and treating the patient, including the simultaneous management of insomnia and depression to improve health outcomes.