This case study analyzes Lisa's substance abuse, identifying mental illness, loneliness, and family conflict as key contributing factors. The study explores the application of trauma-informed care principles in understanding Lisa's situation, highlighting the need for a multidisciplinary approach involving psychiatric nurses, clinical psychologists, social workers, and therapist nurses. It examines how Lisa's failure to adhere to prescribed medication, her isolation, and strained family relationships have likely exacerbated her condition. The case emphasizes the importance of collaboration among healthcare professionals to address Lisa's complex needs, including her mental health issues and substance use. The study also discusses the roles of different types of nurses in Lisa's care, and underscores the importance of creating a safe and supportive environment for her recovery. This case study is a good example of the challenges faced in mental health nursing and the necessity of comprehensive care.