This case study examines Lisa's situation, focusing on her drug abuse and the underlying factors contributing to it. The analysis highlights the significance of mental illness, loneliness, and family conflicts as key issues. It explores the need for a multidisciplinary approach, involving psychiatrist nurses, clinical psychologist nurses, social worker nurses, and therapist nurses. The paper emphasizes the application of trauma-informed care principles, such as safety, trustworthiness, choice, collaboration, and empowerment, in Lisa's treatment. The case study provides insights into how these principles can be implemented to create a supportive and effective treatment plan. The paper also looks at the role of different nurses in addressing Lisa's complex needs, from diagnosing mental health conditions to providing therapy and social support. It underscores the importance of a holistic approach that considers the individual's mental, emotional, and social well-being. Furthermore, it provides a comprehensive understanding of Lisa's case, outlining how various healthcare professionals can work together to help her overcome her challenges and achieve recovery.