This nursing essay examines culturally safe practice for Aboriginal and Torres Strait Islander populations in Australia. It begins by introducing the target group and highlighting health issues such as cardiovascular disease, diabetes, and kidney disease, which are prevalent among this population, particularly in remote areas. The essay then explores the social determinants of health (SDH) and the Etic and Emic views of culture as theoretical frameworks that contribute to health inequalities. The student discusses the importance of patient-centered care, effective communication, and the role of healthcare professionals in providing culturally competent care, specifically in managing T2DM. The essay emphasizes the need for health education, diet planning, and lifestyle modifications to improve health outcomes and reduce health disparities, aligning with the Australian health policy of closing the gap in Indigenous health.