This presentation addresses five critical nursing assessment scenarios, simulating real-world clinical challenges. The first scenario involves a patient experiencing hypoglycemia, highlighting the importance of recognizing adverse changes and providing immediate care. The second focuses on work health and safety, emphasizing adherence to guidelines for a safe working environment. The third scenario explores managing a Muslim patient's refusal to remove her hijab before surgery, underscoring cultural sensitivity and patient advocacy. The fourth scenario involves a 12-year-old Aboriginal girl requiring emergency surgery, emphasizing the need for decisive action in the absence of parental consent. Finally, the fifth scenario addresses a mother with pneumonia and her newborn, highlighting the nurse's role in providing holistic care, including nutritional support and mental health considerations. Each scenario includes a discussion of the nurse's responsibilities, decision-making processes, and relevant references to support the approaches taken in each case.