This essay analyzes the care of a 52-year-old male patient, Mr. X, admitted with depression, hypertension, and hyperlipidemia, incorporating biological, psychological, and sociological perspectives. It explores the patient's anatomy and physiology in relation to his health conditions, including the impact of depression on brain structure and neurotransmitter imbalances. The essay uses the biopsychosocial model to examine the causes of Mr. X's depression, considering his medical history, socioeconomic status, and coping mechanisms. It defines health, well-being, and illness, discussing the adverse effects of depression on the patient and his family, including biological and psychosocial impacts, and explores the application of Erickson’s theory. Furthermore, the essay uses the health belief model to identify facilitators and barriers to health promotion, and the role of nurses in addressing these barriers. The conclusion summarizes the debilitating effects of depression and the importance of comprehensive patient care.