Nursing Assignment: Medication Chart Analysis Report

This nursing assignment analyzes the medications prescribed to a 57-year-old patient, James Murphy, who underwent coronary artery bypass surgery. The assignment is divided into two parts. Part A requires a detailed review of ten medications, including Aspirin, Metformin XR, Ramipril, Metoprolol, Furosemide, Potassium Chloride, Pantoprazole, Atorvastatin, Oxycodone/Naloxone, and Cefazolin, outlining their uses, side effects, interactions, and nursing implications. Part B delves into the mechanism of action of two selected medications, providing in-depth explanations of how they work within the body. The report emphasizes the importance of understanding drug interactions and the implications for patient care, referencing various medical studies and guidelines to support the analysis. The assignment aims to demonstrate a comprehensive understanding of pharmacology and its application in clinical practice, as well as the critical role of nurses in medication management.

Running head: NURSING ASSIGNMENT 1
Nursing Assignment
Student’s Name
Institutional Affiliation

NURSING ASSIGNMENT 2
Part A
Name:
Aspirin.
Use:
Reduction of fever.
Pain reliver (Sumari, Davis, 2019)1.
Reduce swelling and pain in arthritis.
Also used to reduce blood.
Side effects:
Regular headache.
Regular abdominal pain.
Rashes on the skin.
Nausea.
Drowsiness.
Heartburn and gastrointestinal ulcerations.
Interactions:
Care with Omega-3 reach food such as fish oil and eggs. They protect the heart just as aspirin
does.
1 Sumari, Davis (2019). Pain relief for minor aches and pains in the pharmacy. SA Pharmacist's Assistant, 19(1), 6-8.

NURSING ASSIGNMENT 3
Anticoagulants such as apixaban, rivaroxaban or warfarin may increase the risk of complications
such as bleeding if used together with aspirin. However, in some conditions, low dosage of
aspirin may be combined with an anticoagulant such as warfarin.
Nursing implications:
Enough water or fluids should be taken when using aspirin.
For acute management of the heart disease, baby aspirin usually preferred.
If GI discomfort which is unrelieved or ringing in the ears is experienced, then aspirin use should
be discontinued.
Name:
Metformin XR.
Use:
Prevents kidney related diseases.
Controls high blood sugar (Joshi, Lakhani, Siddhpuria, Tandel, & Hajariwala, 2018)2.
Side effects:
Muscle pain.
Physical weakness.
2Dhaval, Joshi B., Lakhani, J. D., Siddhpuria, R. Y., Tandel, H. P., & Hajariwala, N. R. (2018).
A study on drug utilization pattern of metformin and its different formulations used in patients
with type-2 diabetes mellitus in tertiary care teaching hospital. Journal of Integrated Health
Sciences, 6(1), 22.

NURSING ASSIGNMENT 4
Dizziness and chills.
Nausea.
Low levels of vitamin B-12 in the blood.
Interactions:
It should be taken with meals rich in carbohydrates such as beans. This is because they help
reduce bowel side effects or stomach side effects.
Metformin can also interact with drugs such as ethanol, loversol or iodinated contrast media.
Nursing implications:
Glucose and ketones in urine and blood should be monitored regularly.
Alcohol should be avoided when using this drug.
Metformin tablets should be swallowed as a whole.
Name:
Ramipril.
Use:
Used in the treatment of high blood pressure. Helps in the prevention of stroke, kidney related
problems and also heart attacks (Bhat et al., 2019)3.
It also prevents heart related problems.
Side effects:
3 Rahil, Bhat R., Rehman, M. U., Shabir, A., Mir, M. U. R., Ahmad, A., Khan, R., ... & Ganaie, M. A. (2019).
Chemical Composition and Biological Uses of Artemisia absinthium (Wormwood). In Plant and Human
Health, Volume 3 (pp. 37-63). Springer, Cham.

NURSING ASSIGNMENT 5
Yellowing of the skin or eyes which is referred to as jaundice.
Passage of little or no urine.
Fever.
General body weakness.
Coughing.
Headache.
Interactions:
Should not be taken with potassium-rich foods such as green vegetables, bananas or oranges.
Drugs such as aspirin, atorvastatin, amlodipine, Cymbalta, bendroflumethiazide and allopurinol
react with Ramipril when taken together. Furthermore, Ramipril also interacts with some
diseases such as renal dysfunction, bone marrow suppression, hemodialysis, hypotension,
hyperkalemia and angioedema.
Nursing implications:
Swallow as a whole.
Monitor blood sugar level.
Limit alcohol intake.
Impose Abstinence or use of contraception.
Name:
Metoprolol.

NURSING ASSIGNMENT 6
Use:
Treats high blood pressure (Rehman, & Ahmad, 2019)4.
Prevents stroke.
Prevents heart attack.
Prevents kidney related problems.
Chest pain releaver.
Side effects:
Reduces sexual ability.
Drowsiness.
Diarrhea.
Dizziness (Wang, Liu, He, Li, & Zou, 2019)5.
Physical weakness.
Sometimes slow heartbeat may be experienced.
Interaction:
4 Tayyeba, Rehman, & Ahmad, S. (2019). Nardostachys chinensis Batalin: A review of traditional uses,
phytochemistry, and pharmacology. Phytotherapy Research.
5 Yangui, Wang, Liu, C., He, X., Li, Y., & Zou, Y. (2019). Effects of metoprolol, methyldopa,
and nifedipine on endothelial progenitor cells in patients with gestational hypertension and
preeclampsia. Clinical and Experimental Pharmacology and Physiology, 46(4), 302-312.

NURSING ASSIGNMENT 7
Foods rich in potassium should not be taken with metoprolol. This is because metoprolol
happens to be a beta blocker. Cardiac glycosides found in pleurisy root is said to be interfering
with the effects of metoprolol.
SSRI antidepressants, lumefantrine, quinidine and propafenone are among the medications which
may interfere with the work of metoprolol in the body.
Nursing implications:
After one week of therapy, maximal effect on blood pressure is expected.
Heart rate and blood pressure should be monitored carefully.
Lab tests should be performed to come up with the baseline and obtain period evaluation of
blood cell counts, kidney function and the level of sugar in the blood.
If symptoms of mental depression are experienced, then the drug should be withdrawn.
Name:
Furosemide.
Use:
Used to treat edema (Patel, & Singh, 2018)6.
It also helps the body to make more urine which ultimately leads to extraction of water and salt.
Used to treat high blood.
6 Bhishma, Patel P., & Singh, P. K. (2018). Viscum articulatum Burm. f.: A review on its
phytochemistry, pharmacology and traditional uses. Journal of Pharmacy and Pharmacology,
70(2), 159-177.

NURSING ASSIGNMENT 8
Side effects:
Dizziness.
Headache.
Blurred vision.
Dehydration.
Lightheadedness.
Interactions:
Foods rich in potassium should be taken. Also, foods rich in magnesium such as beans, vegetable
and nuts should be taken. This is because they provide enough minerals and vitamins for patients
using furosemide.
Medications that interact with furosemide include aspirin, valsartan, cisplatin, lithium,
cyclosporine, antibiotics such as cephalexin and chloral hydrate.
Nursing implications:
Daily weight, output and intake ratios, lung sounds mucous membrane, the location and amount
of edema should be assessed and monitored.
Patients experiencing confusion, vomiting, nausea paresthesia and muscle cramps should be
assessed.
Blood pressure and pulse should always be monitored before administration.
Allergy should also be assessed.

NURSING ASSIGNMENT 9
Skin rush should be assessed frequently.
Hearing loss and tinnitus should also be assessed.
Name:
Potassium Chloride.
Use:
Prevents hypokalemia which is low levels of potassium in the blood.
Potassium helps organs such as the heart, kidney, nerves, muscles and the body cells to work
properly (Steffensen et al., 2018)7.
Side effects:
Diarrhea.
Upset stomach.
Vomiting.
Nausea.
Slow heartbeat (Lohr, Parsons, Taylor & Morroni, 2018)8.
Chest pain.
7 Inger-Lise, Steffensen, Frølich, W., Dahl, K. H., Iversen, P. O., Lyche, J. L., Lillegaard, I. T. L.,
& Alexander, J. (2018). Benefit and risk assessment of increasing potassium intake by
replacement of sodium chloride with potassium chloride in industrial food products in Norway.
Food and Chemical Toxicology, 111, 329-340.
8 Patricia, Lohr, Parsons, J. H., Taylor, J., & Morroni, C. (2018). Outcomes of dilation and evacuation with and
without feticide by intra-cardiac potassium chloride injection: a service evaluation. Contraception, 98(2), 100-105.

NURSING ASSIGNMENT 10
Allergic reactions such as rashes and blisters may occur.
Interactions:
Should be taken with salt substitutes, snack bars, cereals, soups and potato chips since they also
contain potassium chloride.
Potassium chloride also interacts with aspirin, dextrose, furosemide, Lasix, ibuprofen, fish oil,
calcium, lidocaine, Cymbalta, Lipitor, Nexium, protonix, singulair, vitamin c, synthroid, Xanax
and sodium chloride.
Nursing implications:
Blood pressure should be monitored periodically during the IV therapy.
Serum K should be monitored during therapy periodically.
Renal function and the pH should also be monitored.
Treatment of Toxicity.
Assess body nutrition.
Name:
Pantoprazole.
Use:
Reduces the amount of acid produced in the stomach.
Used in the treatment of erosive esophagitis and Zollinger-Ellison syndrome.

NURSING ASSIGNMENT 11
(Reddy & Jalajakshi, 2018)9.
Side effects:
Blurred vision.
Nausea.
Sweating.
Dry mouth and skin.
Stomach pain.
Trouble during breathing.
Vomiting.
Loss of body weight.
Regular water intake.
Hallucination (Razdan, Viswanathan, & Tusher, 2018)10.
Interactions:
Foods rich in fibre should be taken to prevent constipation.
9 Sunitha, Reddy, & Jalajakshi, B. (2018). Formulation and evaluation sustained release
mucoadhesive gastroretentive pantoprazole sodium sesquihydrate tablets for anti–ulcer. Journal
of Drug Delivery and Therapeutics, 8(6-s), 304-310.
10 Anupriya, Razdan, Viswanathan, R., & Tusher, A. (2018). Pantoprazole-Induced Delirium:
Review of a Case and Associated Literature. Case reports in psychiatry, 2018.

NURSING ASSIGNMENT 12
Some medications need the presence of acid in the stomach hence pantoprazole should not be
taken with these medications. These medications include atazanavir, nelfinavir, rilpivirine,
erlotinib, ampicillin and some azole antifungals.
Nursing implications:
Should not be used as an immediate relief of heartburn.
If used for a long time, it makes the absorption of vitamin B-12 in the body difficult.
Should not be given to patients allergic to any benzimidazole medications.
Name:
Atorvastatin.
Use:
Help to lower cholesterol and fats in the body.
By treating high cholesterol, it lowers the risk of heart related diseases, diabetes or stroke
(Maqsood, Sadeeqa, Ahmad, & Afzal, 2019)11.
It also reduces the level of triglycerides in the blood.
Side effects:
Itching.
Increased heartbeat rate.
Dizziness.
11 Mariam, Maqsood, Sadeeqa, S., Ahmad, M., & Afzal, H. (2019). Efficacy and safety of atorvastatin and
rosuvastatin in ischemic heart disease patients: A prospective study. Tropical Journal of Pharmaceutical Research,
18(7), 1533-1538.

NURSING ASSIGNMENT 13
Fever.
Skin rash.
Hives.
Coughing.
Muscle pains, weakness or swelling (Yang et al., 2018)12.
Difficulty when swallowing.
Physical weakness.
Interactions:
Foods which belong to statin category increase the risk of liver and muscle problems.
Interacts with medications like telaprevir, ritonavir, telithromycin, glecaprevir plus pibrentasvir,
amlodipine, erythromycin, clarithromycin, gemfibrozil and fenofibrate.
Nursing implications:
Atorvastatin may cause hyperkalemia.
Monitoring of CPK levels should be done if the patient starts developing muscle tenderness at
the time of therapy.
Liver functions should first be monitored before commencing the therapy.
12 Qian, Yang, Yin, R. X., Cao, X. L., Huang, F., Zhou, Y. J., & Chen, W. X. (2018). The
ANGPTL4 Variants, Their Haplotypes and G× E Interactions on Serum Lipid Levels, Coronary
Artery Disease, Ischemic Stroke and Response to Atorvastatin Therapy. Coronary Artery
Disease, Ischemic Stroke and Response to Atorvastatin Therapy (July 26, 2018).

NURSING ASSIGNMENT 14
Name:
Oxycodone/ Naloxone.
Use:
Used to treat severe pain (Tovoli et al., 2018)13.
Naloxone is used in the treatment of overdose of narcotic drugs.
It is also used to treat nerve pain.
It is used to treat fibromyalgia.
Side effects:
Chronic constipation (Bantel et al., 2018)14.
Cognitive impairment.
Sweating.
Problems associated with balance.
Delirium.
Interactions:
13 Francesco, Tovoli, De Lorenzo, S., Samolsky Dekel, B. G., Piscaglia, F., Benevento, F.,
Brandi, G., & Bolondi, L. (2018). Oral oxycodone/naloxone for pain control in cirrhosis:
Observational study in patients with symptomatic metastatic hepatocellular carcinoma. Liver
International, 38(2), 278-284.
14 Carsten, Bantel, Tripathi, S. S., Molony, D., Heffernan, T., Oomman, S., Mehta, V., &
Dickerson, S. (2018). Prolonged-release oxycodone/naloxone reduces opioid-induced
constipation and improves quality of life in laxative-refractory patients: results of an
observational study. Clinical and experimental gastroenterology, 11, 57.

NURSING ASSIGNMENT 15
Grapefruit juice should be avoided during administration since it increases the plasma
concentrations of oxycodone. Also, alcohol or alcoholic drinks should not be taken during
therapy since it causes a depressant effect to the opioid analgesics.
Other drugs that reacts with Oxycodone/ Naloxone include: acepromazine, amisulpride,
Amprenavir, acepromazine, amisulpride, atazanavir, benzphetamine, buprenorphine,
butabarbital, chlorpheniramine, chlorzoxazone, ciprofloxacin, clarithromycin, conivaptan,
delavirdine, dexmedetomidine, isocarboxazidKetamine, lisdexamfetamine, mephobarbital,
meperidine, mephobarbital, thiethylperazine, meperidine, mephobarbital, thiethylperazine,
topiramate, zaleplon and zopiclone.
Nursing implications:
Naloxone dose should be administered to the patient from a new auto-injector.
After delivering the first dose of naloxone, seeking for immediate medical assistance should be
done. This is because naloxone’s action is exceeded by most opioids hence resulting to
depression of the respiratory or the Central Nervous System (CNS).
Name:
Cefazolin.
Use:
An antibiotic to treat bacterial infections (Munir et al., 2019)15.
Used during surgeries (before and after) to prevent infections.
15 Muhammad, Munir, Ihsan, A., Javed, I., Ansari, M. T., Bajwa, S. Z., Bukhari, S. N. A., ... &
Khan, W. S. (2019). Controllably Biodegradable Hydroxyapatite Nanostructures for Cefazolin
Delivery against Antibacterial Resistance. ACS Omega, 4(4), 7524-7532.

NURSING ASSIGNMENT 16
Side effects:
Pain and swelling at the injection sites.
Headache.
Gas.
Heartburn.
Fever.
Loss appetite.
Allergic reactions (Kuruvilla et al., 2019)16.
Drowsiness.
Confusion.
Diarrhea.
Interactions:
Use with yoghut, kombucha, kimchi or cheese since they are fermented foods. Lactobacilli in
those foods helps in increasing of the intestines against bacteria.
Interacts with medications like amoxicillin, Coumadin, Cipro, ancef, Colace, gentamicin,
lidocaine, norco, probenecid, toradol, Tylenol, Zofran and vitamin D3.
Nursing implications:
16 Merin, Kuruvilla, Wolf, F., Sexton, M., Wiley, Z., & Thomas, J. (2019). Perioperative use of
cefazolin without preliminary skin testing in patients with reported penicillin allergy. Surgery,
165(2), 486-496.

NURSING ASSIGNMENT 17
Allergic reactions should be monitored first before therapy.
Properly instruct patients to report any signs of infection such as neutropenia or leukopenia.
Seizures should be properly monitored in patients.
Part B
Aspirin
Aspirin falls into the category of non-steroidal anti-inflammatory drugs (NSAIDs).
Aspirin is also a member of the family of salicylates. Often all salicylates have identical salicylic
acid which marks the active agent of the drug. This implies that aspirin has salicylic acid as the
active agent. Salicylic acid is made up of four major parts. These include one carboxyl, one
hydroxyl, two radicals and one benzene ring. In the aspirin (acetylsalicylic acid), the hydroxide
group salicylate is changed into an acetyl group through esterification. Often, the
pharmacological properties and biological actions endorsed to salicylate are identical to those of
Aspirin. However, salicylate has other independent affects because of the presence of its reactive
acetate group (11). Biologically, acetate groups and salicylate are active components which act
independently at different sites. The pharmacological actions of aspirin components can be
illustrated in the figure below.

NURSING ASSIGNMENT 18
Representation retrieved from: (Cadavid, 2017)17
17 Angela, Cadavid P., (2017). Aspirin: The mechanism of action revisited in the context
of pregnancy complications [online]. Retrieved from:
https://www.frontiersin.org/articles/10.3389/fimmu.2017.00261/full
Salicylate group
 The inhibition of binding
of CCAAT to its promoter
region of COX-2 and of
inducible nitrogen oxide
synthase (iNOS) genes.
 Initiation of the
transportation process of
protons across cell
membranes thus resulting
into oxidative
phosphorylation hence
reducing proliferation
which consequently leads
to the death of tumoral
cells.
 Hindering the activation of
genes which take part in
the pathogenesis of
inflammatory response via
blockage of activation by
NF-kB.
Reactive acetyl group
 Permanent inactivation of platelet COX-1
through acetylation of serine-529. This causes
inhibition of thromboxane-A2 production. In so
doing, platelete aggregation and
vasoconstriction induced by this prostanoid is
avoided.
 Elicitation of nitric oxide production from
vascular endothelium through ecetylation of
endothelial NO synthase (eNOS).
 Reduction of inflammation, oxidative stress, and
injury due to induction of enzymatic activity and
expression of the heme oxygenase-1 (HO-1) in
endothelial cells
 Acetylation of multiple cellular proteins such as
human serum albumin, fibrinogen and human
suppressor protein.

NURSING ASSIGNMENT 19
Daily LDA of about 75mg to 100mg are enough to permanently acetylate serine 530 of COX-1,
inhibiting thromboxane –A2 platelet generation, hence causing an antithrombotic effect. On a
similar note, intermediate administering of daily aspirin (six hundred and fifty milligrams to four
grams) inhibit COX-2. Additionally, aspirin can initiate the release of ATL. This lipid mediator
exerts its actions by binding to a G-protein-coupled receptor. The receptor’s identity in this case
is ALXR. A simple concept map for metabolic pathways of AA can be illustrated in the figure
below.
Retrieved from: (Cadavid, 2017)18
Ramipril
Ramipril blocks a body substance that causes the tightening of the blood vessels. As a
result, this drug relaxes the blood vessels. By doing so, blood pressure is lowered, and an
increase in blood supply to the heart is achieved. Some patients with heart failures after
experiencing heart attacks are also subjected to Ramipril. This is because after a heart attack,
18 Ibid

NURSING ASSIGNMENT 20
some cardio muscles become weak and even gets damaged. Over time, these muscles may
worsen and even fail to pump blood.
The first few days after the attack, Ramipril may be introduced to the patient to increase
their survival rate (Darwish, et., al, 2018)19. It can also be used in elderly stroke patients.
Ramipril's pharmacodynamic effects are as a result of the competitive and high affinity of the
reversible binding of the Ramipril to the angiotensin-converting enzyme. Angiotensin-converting
enzyme prevents the formation of the potent substance that vasoconstricts the blood vessels
(Berecek, 2018)20. The enzyme inhibitor present in this drug has a very slow rate of dissociation,
which in turn results in long durations of action and raised potency.
Central Nervous System mechanisms are sometimes involved in the reduction of the
blood pressure effect (Suganthy, et., al, 2016)21. During its distribution in the body, plasma levels
go down. This is usually its first phase. Free Ramipril is then cleared marking the second phase.
19 Mohamed, Darwish, & El-Lateef, A. (2018). Study of potential nephroprotective
effects of Ramipril versus Alpha lipoic acid against Gentamicin induced nephropathy in
rats. Egyptian Journal of Hospital Medicine, 73(10).
20 Mohan, Berecek, King, S. J., & Wu, J. N. (2018). Angiotensin-converting enzyme and
converting enzyme inhibitors. In Cellular and Molecular Biology of the Renin-
Angiotensin System (pp. 183-220). CRC Press.
21 Natarajen, Suganthy, Devi, K. P., Nabavi, S. F., Braidy, N., & Nabavi, S. M. (2016).
Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms
of actions. Biomedicine & Pharmacotherapy, 84, 892-908.

NURSING ASSIGNMENT 21
This starts 9-18 hours after the intake. Tissue binding and dissociation equilibrium phase is the
final phase where elimination occurs at the terminal.
Any form of allergies should be put into account before administering the drug (Levine,
2017)22. Expectant mothers have shown a risk to the fetus when subjected to Ramipril. However,
no risks have been discovered on the risk of a breastfeeding mother subjected to this medication.
References
Bantel, C., Tripathi, S. S., Molony, D., Heffernan, T., Oomman, S., Mehta, V., & Dickerson,
S. (2018). Prolonged-release oxycodone/naloxone reduces opioid-induced
constipation and improves quality of life in laxative-refractory patients: results of an
observational study. Clinical and experimental gastroenterology, 11, 57.
22 Bernard, Levine, (2017, January). Immunochemical mechanisms of drug allergy. In
Immunopharmacology: Proceedings of the Third International Pharmacological Meeting
July 24–30, 1966 (Vol. 11, p. 143). Elsevier.

NURSING ASSIGNMENT 22
Berecek, K. H., King, S. J., & Wu, J. N. (2018). Angiotensin-converting enzyme and converting
enzyme inhibitors. In Cellular and Molecular Biology of the Renin-Angiotensin System
(pp. 183-220). CRC Press.
Bhat, R. R., Rehman, M. U., Shabir, A., Mir, M. U. R., Ahmad, A., Khan, R., ... & Ganaie, M. A.
(2019). Chemical Composition and Biological Uses of Artemisia absinthium
(Wormwood). In Plant and Human Health, Volume 3 (pp. 37-63). Springer, Cham.
Cadavid P. Angela (2017). Aspirin: The mechanism of action revisited in the context of
pregnancy complications [online]. Retrieved from:
https://www.frontiersin.org/articles/10.3389/fimmu.2017.00261/full
Darwish, M. Y., & El-Lateef, A. (2018). Study of potential nephroprotective effects of Ramipril
versus Alpha lipoic acid against Gentamicin induced nephropathy in rats. Egyptian
Journal of Hospital Medicine, 73(10).
Davis, S. (2019). Pain relief for minor aches and pains in the pharmacy. SA Pharmacist's
Assistant, 19(1), 6-8.
Joshi, D. B., Lakhani, J. D., Siddhpuria, R. Y., Tandel, H. P., & Hajariwala, N. R. (2018). A
study on drug utilization pattern of metformin and its different formulations used in
patients with type-2 diabetes mellitus in tertiary care teaching hospital. Journal of
Integrated Health Sciences, 6(1), 22.
Levine, B. B. (2017, January). Immunochemical mechanisms of drug allergy. In
Immunopharmacology: Proceedings of the Third International Pharmacological Meeting
July 24–30, 1966 (Vol. 11, p. 143). Elsevier.

NURSING ASSIGNMENT 23
Lohr, P. A., Parsons, J. H., Taylor, J., & Morroni, C. (2018). Outcomes of dilation and
evacuation with and without feticide by intra-cardiac potassium chloride injection: a
service evaluation. Contraception, 98(2), 100-105.
Maqsood, M., Sadeeqa, S., Ahmad, M., & Afzal, H. (2019). Efficacy and safety of
atorvastatin and rosuvastatin in ischemic heart disease patients: A prospective study.
Tropical Journal of Pharmaceutical Research, 18(7), 1533-1538.
Patel, B. P., & Singh, P. K. (2018). Viscum articulatum Burm. f.: A review on its
phytochemistry, pharmacology and traditional uses. Journal of Pharmacy and
Pharmacology, 70(2), 159-177.
Razdan, A., Viswanathan, R., & Tusher, A. (2018). Pantoprazole-Induced Delirium: Review
of a Case and Associated Literature. Case reports in psychiatry, 2018.
Reddy, M. S., & Jalajakshi, B. (2018). Formulation and evaluation sustained release
mucoadhesive gastroretentive pantoprazole sodium sesquihydrate tablets for anti–
ulcer. Journal of Drug Delivery and Therapeutics, 8(6-s), 304-310.
Rehman, T., & Ahmad, S. (2019). Nardostachys chinensis Batalin: A review of traditional uses,
phytochemistry, and pharmacology. Phytotherapy Research.
Suganthy, N., Devi, K. P., Nabavi, S. F., Braidy, N., & Nabavi, S. M. (2016). Bioactive effects
of quercetin in the central nervous system: Focusing on the mechanisms of actions.
Biomedicine & Pharmacotherapy, 84, 892-908.
Tovoli, F., De Lorenzo, S., Samolsky Dekel, B. G., Piscaglia, F., Benevento, F., Brandi, G., &
Bolondi, L. (2018). Oral oxycodone/naloxone for pain control in cirrhosis:
Observational study in patients with symptomatic metastatic hepatocellular
carcinoma. Liver International, 38(2), 278-284.

NURSING ASSIGNMENT 24
Wang, Y., Liu, C., He, X., Li, Y., & Zou, Y. (2019). Effects of metoprolol, methyldopa, and
nifedipine on endothelial progenitor cells in patients with gestational hypertension and
preeclampsia. Clinical and Experimental Pharmacology and Physiology, 46(4), 302-312.
Yang, Q., Yin, R. X., Cao, X. L., Huang, F., Zhou, Y. J., & Chen, W. X. (2018). The
ANGPTL4 Variants, Their Haplotypes and G× E Interactions on Serum Lipid Levels,
Coronary Artery Disease, Ischemic Stroke and Response to Atorvastatin Therapy.
Coronary Artery Disease, Ischemic Stroke and Response to Atorvastatin Therapy
(July 26, 2018).