This report addresses the critical issue of substance abuse in nursing from a leadership perspective. It begins by defining the problem, highlighting the prevalence of substance abuse among nurses, and the potential impact on patient care and safety. The report delves into the causes of substance abuse, including factors such as job stress, anxiety, and access to controlled substances. It then explores the role of nurse leaders in addressing this issue, including strategies for prevention, early intervention, and support for nurses struggling with addiction. The report includes a review of relevant literature, providing evidence-based solutions and best practices for creating a supportive and safe work environment. Furthermore, it proposes specific recommendations for nurse leaders to reduce the incidence of nurse impairment and promote a culture of wellness and accountability within healthcare settings. The report concludes with a call to action, emphasizing the importance of proactive measures and ongoing support to address this significant challenge in the nursing profession.