This report delves into Hildegard Peplau's Theory of Interpersonal Relations, examining its significance in nursing practice. It begins with a comprehensive description of the theory, its origins, and its scope within the nursing field. The report identifies key concepts such as nursing practice, patient, health problems and society, and environment. It then explores how the theory is applied in nursing research, analyzing two published studies that utilized Peplau's framework to improve patient care, especially in the context of self-care for diabetic and psychiatric patients. Furthermore, the report discusses the theory's implications for nursing practice across educational, clinical, and research settings, including phases of interpersonal relationships and operational definitions of key concepts. The report concludes by highlighting the importance of therapeutic relationships between nurses and patients and how this theory can lead to improved patient outcomes. The assignment also includes an evaluation of the theory’s accuracy, generalizability, strengths, weaknesses, and congruence with current nursing standards.