This report addresses obesity prevention in healthcare, focusing on two key areas: strategies to prevent obesity and the genetic determinants of obesity. The first part reviews a Cochrane library review on the effectiveness of diet and physical activity in preventing childhood obesity. The review indicates that while these strategies are often implemented, there is a lack of substantial evidence supporting their effectiveness, highlighting the need for further research. The second part of the report delves into the role of genes in the development of overweight and obesity. It discusses the inherited nature of obesity, noting that genetic factors can account for a significant variation in body mass within a population. The report emphasizes that even with similar lifestyles, genes can influence obesity, and that environmental factors like exercise and diet can also play a role in gene expression. The report concludes by referencing several studies that support these findings.