This report details a database search conducted to investigate the impact of palliative care on the quality of life of cancer patients compared to conventional care. The search utilized the Medline database, employing various search strings with and without the MeSH thesaurus function. The process involved iterative refinement of search terms, including keywords like "quality of life," "palliative care," and "cancer." The search results were analyzed, and relevant articles were identified. The report highlights the importance of formulating effective search terms and understanding the database's functionalities. The report also discusses the challenges encountered and the strategies used to optimize the search process, including the use of MeSH terms and filters to narrow down the results. The findings emphasize the value of palliative care and the importance of efficient database searching skills for healthcare research. The report concludes by providing insights for individuals new to database searching, offering guidance on keyword selection, understanding database features, and refining search strategies to achieve optimal results. The report includes a discussion of two relevant articles and their findings.