This report provides an overview of palliative management of pain in terminally ill patients, emphasizing the importance of addressing pain to improve the quality of life for both patients and their families. It begins by defining pain and highlighting its prevalence among terminally ill individuals, noting the physical, mental, and emotional impact it has on patients. The report details the palliative care approach to pain management, starting with a comprehensive pain assessment that considers the patient's history, behavior, and individual needs. It discusses the establishment of treatment goals focused on minimizing pain, addressing spiritual and psychological components, and supporting the family. The report covers both pharmacological interventions, such as the WHO analgesic ladder using opioids and non-opioids, and non-pharmacological approaches, including physical, psychological, and complementary therapies. Additionally, it emphasizes the importance of a collaborative, interdisciplinary team in providing holistic care and supportive interventions to enhance the patient's comfort and overall well-being.