Comprehensive Analysis: Breast Cancer Pathophysiology and Treatment

This report provides a comprehensive overview of breast cancer, beginning with an introduction to cellular processes and the nature of disease. It then delves into the specifics of breast cancer, including its prevalence, particularly in Australia, and the associated risk factors such as age, genetic mutations (BRCA1 and BRCA2), and reproductive history. The report details the pathophysiology of breast cancer, explaining how malignant tumors develop and the role of DNA and genetic mutations, including estrogen exposure. Clinical manifestations are discussed, emphasizing the importance of breast examinations and self-awareness. Furthermore, the report outlines various treatment options, including screening tests, lifestyle modifications (such as alcohol moderation), and hormone therapy considerations. Finally, the report concludes with implications for clinical practice and the rising incidence of breast cancer, emphasizing the need for early detection and appropriate treatment strategies. References to supporting literature are included.

CONCEPT OF
PATHOPHYSIOLOGY

Content
• Introduction
• Pathophysiology
• Treatment
• Implication
• Conclusion
• References

INTRODUCTION
• There are number of trillion of cell in the body. The
cell which is highly cell cycle that control their
growth, maturity, division, and also it is associated
with the death.
• As per this, disease is known as pathogen which
enter in body from the externally area and may
affect the region such as various organ. This is also
started from the internal source which is usually
caused by the cell in the phase of cell.

Disease overview
• Breast cancer is now common disease which is leading cause of cancer in mortality in women in Australia.
Approximately, 1 million new breast cancer cases which is diagnosed in 2009.
• There is almost half of the cancer of breast cases which is nearly 60 percent of the death occurring that is lower
income of the state and countries such as Australia. Low and middle income countries which s low in their
infrastructure of health.
• That is goal of improving breast cancer which detectable, diagnosis and treatment. For an Australian, the lifetime
risk develop the raise of breast cancer is 13 percent.

Risk factor of breast cancer
• Getting older: The risk which is associated with enhance with the growing age and number of cancer are
diagnosed with after the age of 50.
• Genetic mutation: There changes are created mutation to certain gene which is such as BRCA1 and BRCA2
which is inherited for these genetic changes with higher risk of breast and ovarian cancer.
• Reproductive history: Early menstrual and their period age which is starting from 12 and starting with the factor
of menopause. Raising which is based on their risk of breast cancer.

Pathophysiology of breast cancer
• The breast cancer which is malignant in nature they
are form in the form in tumor. That is start cell of the
breast cancer. Like such as cancer in which is there
are various several factor which is associated with
getting breast cancer.
• This is also a part of DNA and genetic mutation
which can lead mutation can also be susceptible for
breast cancer which is linked to estrogen exposure
and this is also create complication.
• They are damage to the DNA and genetic mutation
can lead to the complication which is created by
breast cancer.

Clinical manifestations with pathophysiological rationale
• Utility of the breast cancer which possessed by the breast examination is an controversial as the benefits of the
deceased mortality has not been elaborated as much in this case.
• As per this the various number of clinical significance provide the brief outlet in this by performing the monthly
test of BSE to become familiar with their normal anatomy and physiology them as regards to their own sector of
healthcare.
• The clinical manifestation of the clinical which show the recommendation of clinical breast self awareness in
order to create the rationale.

Treatment options
• Ask doctor for test: There are various test which is used to provide the screening which is associated with this,
some of the breast exam and mammogram. The benefits and risk of screening.
• Drink alcohol in moderation: Control the amount of alcohol which is not more than the ability of the person and
individual.
• Limit the postmenopausal hormone therapy: The combination of the hormone which my increase in the factor of
risk and formulate more complication in this.

Implications for clinical practice
• Breast cancer which is ongoing problem which is
help in diagnose of neoplasm and principle which is
responsible for the most of death in women in
Australia.
• There are number of people which is more than 40.
Young women also tumor with more involvement in
aggressive feature and also this is related with
address according.

CONCLUSION
• As per the above discussion this is well examine the
breast cancer is raising now day in women in more
radially and cause number of complication.
• The overall pathophysiology analyze that the
development of abnormal cell lead cancer.

REFERENCES
• Waks, A. G., & Winer, E. P. (2019). Breast cancer treatment: a review. Jama, 321(3), 288-300.
• De Cicco, P., Catani, M. V., Gasperi, V., Sibilano, M., Quaglietta, M., & Savini, I. (2019). Nutrition and breast
cancer: a literature review on prevention, treatment and recurrence. Nutrients, 11(7), 1514.
• Khan, S., Islam, N., Jan, Z., Din, I. U., & Rodrigues, J. J. C. (2019). A novel deep learning based framework for
the detection and classification of breast cancer using transfer learning. Pattern Recognition Letters, 125, 1-6.