This report provides an overview of clinical effectiveness and its impact on patient safety within healthcare settings. Clinical effectiveness, defined as ensuring clinical safety during the provision of services, encompasses clinical effectiveness, patient safety, and patient experience. The report details how clinical effectiveness is measured by the extent to which interventions achieve their intended outcomes and emphasizes the importance of not only the end result but also the means to achieve it. Patient safety covers infrastructure, design, and technology, while patient experience reflects the patient's feelings about their care. The application of value and quality, achieved through stakeholder dedication, further enhances clinical effectiveness, ultimately working to improve patient safety in healthcare centers.