Comprehensive Report: Personalized Medicine in Cancer - A Review

This report provides a comprehensive overview of personalized medicine in cancer, emphasizing its basis in genetic characteristics and specific diseases. It discusses targeted therapies, such as those used for HER2-positive breast cancer, and the importance of understanding gene-drug interactions (pharmacogenomics). The report addresses ethical considerations, including incidental findings and the need for standard treatment guidelines. It highlights precision medicine approaches, where treatments are selected based on genetic understanding, and the importance of considering patient medical history and potential adverse effects. The report concludes that personalized medicine offers newer treatments that target abnormal proteins or mutated genes, potentially leading to improved cancer prevention and treatment outcomes. It also references studies and the role of ethical issues in the field.

Summary
In accordance to studies cancer is
demonstrated as a disease in which the abnormal
cells multiply uncontrollably and invade close
tissues. The term personalized cancer medicine this
means medical care is based on genes and on
specific disease. The targeted specific proteins and
genes which allow cancer to survive and grow,
bladder cancer, cervical cancer, endometrial
cancer, esophageal cancer these are examples of
personalized cancer medicine.
Introduction
Personalized medicine describes that medical care
could be based on genes and specific disease, this
term comes by learning going through human
genes or the genes involving in different cancers,
learning or studies are the terms which helps
researchers to make effective treatments. In this
process genes are the important information’s that
instruct body cells how to develop and grow. There
are many types of cancers which involves
particular genes as well as they affect, such kind of
As per studies cancer is distraught by many
ethical issues they are dilemmas may occur
during diagnosis, expanse in patient
information, or rather than this planning of
treatment and after that to follow up given
procedure such kind of issues are bringing
concerns for oncologist in their daily
practice.
Conclusion
As per discussed the term personalized
medicine in cancer is mainly defines
medical care which is based on genetic
characteristics., cancer can be treated by
different ways such as surgery,
chemotherapy but personalized medicine is
those in which doctors are allow to add
different newer treatment, which targets on
abnormal proteins or mutated genes in this
way cancer can be cured and prevented.
Personalized medicines are those which
increases impacts on health by increasing
patient understanding of severe side
effects, or this process focus on clinical.
References
Cheng, T. and Zhan, X., 2017. Pattern recognition for
predictive, preventive, and personalized medicine in
cancer. EPMA Journal, 8(1), pp.51-60.
Samuel, M. and Gabrielsson, S., 2019. Personalized
medicine and back–allogeneic exosomes for cancer
immunotherapy. Journal of internal medicine.
Lukanović, D. and et.al., 2020. The contribution of
copper efflux transporters ATP7A and ATP7B to
chemoresistance and personalized medicine in ovarian
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p.110401.
Cartron, P.F., Cheray, M. and Bretaudeau,
Ethical arguments
Personalized medicines this term is usually
defined as medical care which is managed
according to personal genome, if the genetic
variants of peoples are known then it would
be easy for the clinicians to determine what
kind of treatments are needed which could
improve health outcomes. There are few
examples of personalized medicine those are
using targeted therapies for the treatment of
specific cancer cells, by using tumour of
market testing cancer is diagnosed for such
as human epidermic growth factor of
receptor2 of (HER2) – positive breast cancer.
There is another challenge of personalized
medicine that is incidental findings in ethics,
as mentioned that personalized medicines are
based on genetic characteristics which is
internal for every individual as well as there
are external influences which include
environmental factors and poverty but these
are not considered even though they are
having an impact on an individuals health, in
the process of personalized medicine ethics
might give several benefits from different
perspectives or else from possible
vulnerabilities, during health issues
medicines are approached in advance due to
this reflect upon , potential concerns are
measured.
Personalized Medicine in Cancer
Guideline for personalised medicine
A guideline in personalized medicine in
cancer is known as standard treatment
guideline which are based on the
management, diagnosis, treatment on specific
healthcare areas. These guidelines evaluate
quality evidence as well as estimate current
data for the diagnosis, prevention, and
prognosis and this also includes dosage of
medications. Precision medicines are those
treatments are selected by doctors and these
treatments are given on the genetic
understanding. Providing medicines for
bladder cancer, brain cancer, cervical cancer
these are the personalized cancer is called
medical guideline studies shows that genes
mainly affects to the response of drugs, and
this is known as pharmacogenomics , while
drugs are taken they affects genes and makes
certain difference so there should be proper
medications based on patient medical history
as well as be aware of adverse effects. It's
very essential to know how well drug is
working and how much safe it is.