This assignment focuses on applying the PICO (Patient/Problem, Intervention, Comparison, Outcome) framework to investigate the impact of preoperative breathing exercises on reducing postoperative pulmonary complications in patients undergoing cardiac surgery. The assignment includes developing a PICO research question, identifying relevant search terms, creating a systematic search strategy using Boolean operators, and documenting the search process in Medline. It also involves selecting appropriate study types to address the research question and refining the search based on inclusion criteria such as gender, age range, publication dates, and language. The assignment demonstrates a structured approach to evidence-based practice by translating a clinical scenario into a searchable question and planning a systematic search for relevant research articles.