This presentation explores the relationship between tobacco smoke and cardiovascular disease among young adults aged 16-24, utilizing the PICO framework to structure the analysis. It begins by identifying the research area, population of interest, and relevant health promotion activities, particularly awareness programs aimed at reducing smoking. The PICO framework focuses on young adults, the impact of awareness programs (intervention) compared to non-intervened groups, and the desired outcome of decreased smoking rates. Literature review highlights the effectiveness of educational programs and governmental regulations in curbing smoking habits. Key research questions include the efficacy of educational programs, the correlation between smoking and heart disease, and the impact of smoking regulations. Alternative terms are provided for population, intervention, and outcomes to broaden the scope of the research. This presentation aims to provide insights into strategies for reducing smoking rates and improving cardiovascular health among young adults.