This report examines the principles of trauma-informed care and practice, focusing on a case study involving a patient experiencing mental health challenges, including substance use, paranoia, and auditory hallucinations. The report analyzes how issues such as medication relapse, paranoia, and auditory commands contribute to the patient's problematic substance use. It then delves into the core principles of trauma-informed care, including safety, trustworthiness, transparency, mutuality, and collaboration, illustrating their application through the case study. The report emphasizes the importance of collaboration between mental health nurses, counselors, and other professionals to develop patient-centered care plans, address the patient's specific needs, and mitigate potential risks. The report also discusses how the principles of trauma-informed care can be applied by nurses when engaging with consumers and members of a multidisciplinary team to improve patient outcomes and ensure comprehensive care.