This report, prepared for PPMP20012, explores the critical role of Project Management (PM) application systems, particularly Project Management Information Systems (PMIS), in achieving successful project outcomes. It emphasizes the importance of selecting appropriate PM systems, detailing their benefits, such as improved collaboration, agile processes, and enhanced stakeholder communication. The report highlights how PMIS aids in efficient planning, execution, and monitoring, enabling project managers to stay on schedule and within budget. It also acknowledges the challenges associated with PMIS implementation, including costs, training requirements, and the need for compatible hardware. Furthermore, the report references relevant readings, including SEBoK, Kerzner, and AS/NZS standards, to provide a comprehensive understanding of PMIS within the broader context of project, program, and portfolio management. Finally, the report outlines the significance of systems thinking for project, program and portfolio managers.