PY3001 Capstone Project: Investigating Resveratrol Health Benefits

This document presents a comprehensive capstone project from a student, focusing on the health benefits of Resveratrol. The project includes a detailed research log documenting the sources used, such as Google Scholar and CINAHL, with specific search terms and identified resources related to Resveratrol's impact on cardiovascular disease, cancer, asthma, kidney disease, and joint pain. A reflective log critically assesses the usefulness of each resource, discussing search strategies, challenges, and insights gained. The project also encompasses a research diary and reflective log, showcasing the student's ability to gather information and reflect on the research process, including the effectiveness of different resources and search methods. The student reflects on the usefulness of various articles and databases, highlighting the challenges encountered and the knowledge acquired during the research process. The project aims to develop communication, research, and organizational skills, demonstrating the student's capacity for independent research and critical analysis within the field of pharmacy.

Student Name: Student ID no:
Module Title:
Professional & Scientific Skills for Pharmacy
Module Code: PY3001
Assessment Title:
Capstone Project - Reassessment
Assessment weighting: 30%
Submission Date:
Monday 19th August 2019
(Electronically via - Canvas)
Marks will be released after the
exam boards in early
September.
Learning outcomes: Assessment Task:
Use a range of analytical techniques
(including ICT) to process and display data
from laboratory work and secondary
sources.
Summative practical lab reports (S)
and formative lab exercises (F).
Capstone project (S)
Data analysis section of the written
exam (S)
Retrieve, evaluate and present information
in a variety of formats, including writing,
orally and via electronic media
Summative practical lab reports (S)
and formative lab exercises (F),
capstone project (S).
Demonstrate an understanding of the
professional role and responsibilities of
Comprehension section of exam (S)
PY3001: Professional & Scientific Skills for Pharmacy
Assessment Front Sheet

pharmacists. Capstone project (S)
Identify and describe the wider factors that
influence current scientific and pharmacy
practice
Formative study skills exercises (F),
Comprehension section of exam (S)
and the Capstone project (S).
Use a range of analytical techniques
(including ICT) to process and display data
from laboratory work and secondary
sources.
Summative practical lab reports (S)
and formative lab exercises (F).
Capstone project (S)
Data analysis section of the written
exam (S)
Plagiarism statement:
You are reminded that plagiarism (unacknowledged use of the words or ideas of
others) is not acceptable. Students found to have plagiarised another person’s
work will have their assessment graded as a fail and may face disciplinary action.
Please sign below to indicate that this is your own original work.
Student’s signature: ………………………………………………………………………..
Late submission: Work submitted more than seven days after the deadline, without
extenuating circumstances, will be given a mark of zero and the maximum overall mark for the
module will be capped at a maximum of 40%.
HE Front Sheet Form 1 QLAS June 2013

Faculty of Science, Engineering and Computing
PY3001: Professional & Scientific Skills for Pharmacy
Capstone Project:
Poster and Abstract
(Reassessment)
2018-2019
Deadline: 19th August 2019
Module weighting: 30 %
Submission details: Electronic submission on Canvas
Please submit unto Canvas both your poster and an
electronic version of your capstone research diary
Introduction

As part of this assessment you will be required to:
1. Produce a scientific poster based on the given capstone topic:
“The health benefits of Resveratrol”
2. Write an abstract based on your poster.
3. Complete a Research diary & Reflective log, as you research your topic.
The ability to undertake research and convey this information is essential in Higher
Education. Therefore this exercise is designed to support you in subsequent study beyond
your Foundation year.
Module Learning Outcomes assessed in this piece of coursework
 To develop your communication skills by presenting a poster.
 To introduce reflective practice and its value in research.
 To develop your ability to plan and organise your work.
 To reinforce your ability to retrieve information.
 To develop your ability to work independently.

Section 1: Research Log (Finding / Gathering information)
Record the various primary, secondary and tertiary sources used to research the capstone topic, in the table
below:
Date Resources Used
(Name of library database,
online resources etc)
Search Terms Used
(Keywords, subject tags)
Relevant Resources Identified
(List all materials identified e.g. Name of a
book; Web-link; Journal; Professional Bodies)
Google Scholar Resveratrol sources He S, Yan X. From resveratrol to its derivatives:
new sources of natural antioxidant. Current
medicinal chemistry. 2013 Mar 1;20(8):1005-17.
Google Scholar Resveratrol benefits in healthcare Stanevičienė I, Mongirdienė A, Bernatonienė J.
Multiplicity of effects and health benefits of
resveratrol. Medicina. 2016 Jun;52(3):148-55.
Google Scholar Resveratrol in kidney disease Gan Y, Tao S, Cao D, Xie H, Zeng Q. Protection of
resveratrol on acute kidney injury in septic rats.
Human & experimental toxicology. 2017
Oct;36(10):1015-22.
CINAHL Resveratrol in cardiovascular disease Lieben Louis X, Meikle Z, Chan L, DeGagne G,
Cummer R, Meikle S, Krishnan S, Yu L, Netticadan
T, Wigle JT. Divergent Effects of Resveratrol on

Rat Cardiac Fibroblasts and Cardiomyocytes.
Molecules. 2019 Jan;24(14):2604.
CINAHL Resveratrol in asthma Kim HY. Resveratrol in asthma: a French paradox?.
Allergy, asthma & immunology research. 2017 Jan
1;9(1):1-2.
CINAHL Resveratrol in cancer Salehi B, Mishra A, Nigam M, Sener B, Kilic M,
Sharifi-Rad M, Fokou P, Martins N, Sharifi-Rad J.
Resveratrol: A double-edged sword in health
benefits. Biomedicines. 2018 Sep 9;6(3):91
Google Scholar Resveratrol in cancer Carter LG, D'Orazio JA, Pearson KJ. Resveratrol
and cancer: focus on in vivo evidence. Endocrine-
related cancer. 2014 Jun 1;21(3):R209-25.
Google Scholar Resveratrol in the treatment of cardiovascular
diseases
Raj P, Louis XL, Thandapilly SJ, Movahed A,
Zieroth S, Netticadan T. Potential of resveratrol in
the treatment of heart failure. Life sciences. 2014
Jan 30;95(2):63-71.
Google Scholar Resveratrol in the treatment of asthma Ni ZH, Tang JH, Chen G, Lai YM, Chen QG, Li Z,
Yang W, Luo XM, Wang XB. Resveratrol inhibits

mucus overproduction and MUC5AC expression in
a murine model of asthma. Molecular medicine
reports. 2016 Jan 1;13(1):287-94.
CINAHL Resveratrol protects from joint pain Wang ZM, Chen YC, Wang DP. Resveratrol, a
natural antioxidant, protects monosodium
iodoacetate-induced osteoarthritic pain in rats.
Biomedicine & Pharmacotherapy. 2016 Oct
1;83:763-70.
Add extra rows as required
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insert additional rows to the
table as you require them.

Section 2: Reflective Log
Reflect and discuss the usefulness of the identified resources
Resource Used
Reflect and assess the usefulness of the identified resources
(Did you adjust your search strategy at all? Explain why this was necessary. Reflect on the resources you
used, the difficulty on using them and what you learned about using resources for your research)
Lieben Louis X, Meikle Z,
Chan L, DeGagne G,
Cummer R, Meikle S,
Krishnan S, Yu L, Netticadan
T, Wigle JT. Divergent
Effects of Resveratrol on Rat
Cardiac Fibroblasts and
Cardiomyocytes. Molecules.
2019 Jan;24(14):2604.
This resource was used in order to know about the role of resveratrol in cardiovascular diseases. According to me,
cardiovascular problem is the most common illness suffered by numerous individuals worldwide. Hence, I had to
know how Resveratrol helps in treating cardiovascular disease. I opted for this article as it is explained really well but
the authors did not provide accurate evidences.
Some of the key terms that were used for this literature search were namely; Resveratrol, sources, benefits, asthma,
cardiovascular, joint pain, cancer. These search terms were combined with Boolean operators 'AND' and 'OR' that
helped in narrowing and broadening the search hits.
Articles published in English language, from 2016 till 2019 were selected by placing a limiter on the publication date.
Salehi B, Mishra A, Nigam
M, Sener B, Kilic M, Sharifi-
Rad M, Fokou P, Martins N,
Sharifi-Rad J. Resveratrol: A
Going through this research article helped me in gaining knowledge about the befit of Resveratrol in cancer. Cancer is
a dreadful disease and many people lose their life due to lack of treatments. There are also very less drugs available in
the market which can cure cancer. Hence, I was very interested in knowing about how Resveratrol help in curing
cancer or help in the risk of this disease. This research article was well structured with all the different kinds of cancer

double-edged sword in health
benefits. Biomedicines. 2018
Sep 9;6(3):91
and whether all cancers can be cured with this drug or not. However, I feel there was not appropriate conclusion
regarding its usage in cancer therapy.
Gan Y, Tao S, Cao D, Xie H,
Zeng Q. Protection of
resveratrol on acute kidney
injury in septic rats. Human
& experimental toxicology.
2017 Oct;36(10):1015-22
This resource was used by me in order to gain knowledge for the treatment of kidney diseases using Resveratrol. This
article mainly focusses on one of the benefit of Resveratrol. It explains well how it can be used as a medicine in order
to treat kidney diseases.
Kim HY. Resveratrol in
asthma: a French paradox?.
Allergy, asthma &
immunology research. 2017
Jan 1;9(1):1-2.
By reading this research paper, I came across the use of Resveratrol in asthma with proper evidences. Asthma is again
a very common disease suffered my many around the globe. I was keen on knowing how this agent will help in curing
Asthma. This research article was referenced very well and also the explanations were accurate. However, the
problem lied in the structure of this article. According to me, this article was not well structured.
Stanevičienė I, Mongirdienė
A, Bernatonienė J.
Multiplicity of effects and
health benefits of resveratrol.
This resource was used so that I come to know about the benefits of Resveratrol in healthcare which is the main topic
of my poster presentation. In my last article, I came to know that Resveratrol serves many benefits to the health but
this article helped me in knowing all the benefits in details. I found it to be a well- researched article. The authors have
provided numerous evidences regarding the detailed explanation of all the benefits served by Resveratrol to our

Medicina. 2016
Jun;52(3):148-55.
health.
Ni ZH, Tang JH, Chen G, Lai
YM, Chen QG, Li Z, Yang
W, Luo XM, Wang XB.
Resveratrol inhibits mucus
overproduction and
MUC5AC expression in a
murine model of asthma.
Molecular medicine reports.
2016 Jan 1;13(1):287-94.
Many individuals around the globe suffer from asthma. Natural products are the best medicines. Hence, this research
paper helped me in improving my learning on the usefulness of Resveratrol in asthma. It also portrays the murine
model of asthma which helped me in understanding the treatment procedure better. I found this model in the previous
article itself but it was not explained well in the last article. Hence to gain more knowledge about this model and the
benefit of Resveratrol in Asthma I went through this article. However, also unlike the first one, I found this to be well-
structured article as well.
Wang ZM, Chen YC, Wang
DP. Resveratrol, a natural
antioxidant, protects
monosodium iodoacetate-
induced osteoarthritic pain in
rats. Biomedicine &
Pharmacotherapy. 2016 Oct
This research article helped me in knowing more about the role of Resveratrol in the diagnosis of joint pain or
arthritis. Joint pain is suffered by many individual mainly in adults. Hence, the adults require its medication on a daily
basis. According to me, Resveratrol would be a good one if it served in curing joint pain as this is mainly obtained
from natural sources. Hence, to research about this more, I opted for this article and studied it thoroughly.

1;83:763-70.
Carter LG, D'Orazio JA,
Pearson KJ. Resveratrol and
cancer: focus on in vivo
evidence. Endocrine-related
cancer. 2014 Jun
1;21(3):R209-25.
This research article helped me in gaining more knowledge about the usefulness of Resveratrol in cancer and the
application of it in cancer therapy. I opted for this research paper as I found it to be a well-researched article and the
authors provided numerous evidences which they helped in their research study.
Imposing a limitation on the publication date prevented extraction of articles that were relevant to the topic of interest.
Thus, the publication year was changed from 2016 to 2013 that helped in retrieving several articles published on or
after 2013. The remaining parameters were unchanged.
Raj P, Louis XL, Thandapilly
SJ, Movahed A, Zieroth S,
Netticadan T. Potential of
resveratrol in the treatment of
heart failure. Life sciences.
2014 Jan 30;95(2):63-71.
Cardiovascular disease is one of the most dreadful diseases and in many countries death rates are increasing because
of it. Hence, it was important for me to know more about the uses of Resveratrol in the treatment of cardiovascular
disease mainly in the diagnosis of heart failure. In my last article I was not satisfied as there was lack of evidences.
Hence, in order to recheck their studies and gain my knowledge I opted for this article as I found this to be well
researched with accurate evidences.
He S, Yan X. From
resveratrol to its derivatives:
new sources of natural
antioxidant. Current
medicinal chemistry. 2013
This material was used in my poster in order to determine the sources of Resveratrol. It helped me in knowing its
important causes. This research article is very well researched about the sources from which we can obtain
Resveratrol. I also learned that Resveratrol has many benefits in the recovery process of our health. Though it is not
mentioned well in this article but the authors provided references about their research on the above.

Mar 1;20(8):1005-17.