SBI241 Assessment 2: Pathophysiological Basis of Hypertension in CKD

This case study examines a 49-year-old male farmer presenting with symptoms indicative of chronic kidney disease and hypertension. The solution identifies the pathophysiological basis of hypertension in the context of chronic kidney disease, focusing on mechanisms like sodium dysregulation, increased sympathetic nervous system activity, and alterations in the renin-angiotensin-aldosterone system. It also determines the patient's stage of chronic kidney disease (Stage 3a) and outlines the main management approaches, including blood pressure control using ACE inhibitors or ARBs. The analysis considers the patient's medical history, lab results, and potential complications associated with hypertension and CKD.