This report provides a comprehensive overview of securing Internet of Things (IoT) and cyber-physical assets. It begins with an introduction to IoT, its growth, architecture, and associated vulnerabilities. The report then explores cyber-physical assets, digital twins, and the need for a robust IoT security architecture. Key areas covered include vulnerabilities in IoT and cyber-physical assets, the use of cryptography in designing protection solutions, and strategies for securing the environment. The report also delves into selecting the right cryptographic solutions and designing effective IoT security architectures. It emphasizes the importance of real-time communication, data accuracy, and privacy within the IoT environment. The report also discusses various terminologies, including sensor devices, transport layers, host processors, and storage units. The growth and evolution of IoT, including the increasing demand for device connectivity and machine-to-machine communication, are also analyzed. The report concludes with a discussion of the system architecture for IoT and its vulnerabilities.