This nursing case study examines the case of Kathleen Johnson, a patient who underwent a sleeve gastrectomy. The assignment delves into the aetiology and pathophysiology of her morbid obesity and type 2 diabetes, highlighting the role of factors like endoplasmic reticulum stress, tobacco, and alcohol addiction. It then analyzes the patient's post-operative complications, including respiratory distress, elevated heart rate, hypertension, and pain, utilizing the ABCDE approach for assessment. The study explores the underlying pathophysiology of these complications and outlines the nursing care priorities, such as managing respiratory and cardiovascular issues, and pain. Furthermore, it emphasizes the importance of interdisciplinary healthcare, including dieticians, alcohol and drug counselors, and social workers, to ensure comprehensive patient recovery and well-being. The case study concludes with a summary of the key findings and the significance of interdisciplinary interventions.