This report provides a comprehensive analysis of AstraZeneca's strategic management, focusing on internal factors, business strategies, and sustainability practices. It begins with an introduction to strategic management and its importance in the current business environment, followed by an examination of AstraZeneca's internal analysis, including a SWOT analysis to identify strengths, weaknesses, opportunities, and threats. The report then delves into the VRIO model to assess the company's resources and capabilities, determining their value, rarity, imitability, and organizational structure. Furthermore, it explores AstraZeneca's business strategies, such as return to growth and achieving scientific leadership, and how these strategies are adapted in response to challenges like the COVID-19 pandemic. The concept of sustainability is also discussed, highlighting its three pillars and AstraZeneca's approach to achieving sustainability goals through models like Porter’s Five Forces. The report concludes by emphasizing the interconnectedness of strategic management, resource capabilities, and sustainability in ensuring AstraZeneca's competitiveness in the pharmaceutical industry.