This dissertation investigates the significant relationship between occupational stress and healthcare workers in Saudi Arabia, focusing on a case study at Kings Hospital. The research employed a quantitative research design, utilizing a cross-sectional descriptive analysis with surveys distributed to 50 healthcare professionals, including nurses, doctors, and staff with at least five years of experience. The study's findings, supported by statistical analysis, reveal a significant correlation between occupational stress and both physical and psychological health, with nurses disproportionately affected. The research highlights the increased risk of stress, anxiety, depression, and decreased job satisfaction, potentially leading to higher turnover rates, particularly among nursing staff. The study underscores the need for further research with open-ended questionnaires to gain a comprehensive understanding of the issue across various healthcare organizations in Saudi Arabia. The study also includes a detailed literature review, methodology, survey results, and statistical analysis.